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MetabolomicsChemerin sustains the growth of spongiotrophoblast and sinusoidal trophoblast giant cells through fatty acid oxidation

Background: Placental metabolic abnormalities are linked to pregnancy complications such as preeclampsia, gestational diabetes mellitus and fetal growth restriction. However, little is known about how the metabolic processes regulate placental development and trophoblast differentiation. The adip...

2025-06-13 | MTBLS12552 | MetaboLights
TranscriptomicsComparison of gene expression between Human umbilical vein endothelial cells and Human liver sinusoidal endothelial cells
To identify leukocyte adhesion receptors which differentially regulate recruitment in human liver sinusoidal endothelial cells compared to a protoptypic venular endothelium Gene expression was measured in four groups Group 1: cultured human liver sinusoidal endothelial cells (HSEC) Group 2: cultured...
ORGANISM(S): Homo sapiens 
2016-10-24 | E-GEOD-78020 | biostudies-arrayexpress
TranscriptomicsNormal and injured liver sinusoidal endothelial cells
Comparison of C57BL/6J 8-10 weeks male mouse liver sinusoidal endothelial cells (LSEC) from normal liver and from liver injured by carbon tetrachloride administration. Keywords: other
ORGANISM(S): Mus musculus 
2004-10-01 | E-GEOD-1689 | biostudies-arrayexpress
TranscriptomicsRole of zyxin in the tension-induced expression change in endothelial cells
One of the hallmarks in hypertension is a pressure-induced change in endothelial cell phenotype. A cytoskeletal protein zyxin, which was seen to translocate from focal adhesion contacts to the nucleus in response to the increased wall tensionis, mediates the tension-induced endothelial signaling. Mi...
ORGANISM(S): Homo sapiens 
2010-08-16 | E-GEOD-17814 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse P6 retinal endothelial cells extracted from wildtype and dll4 heterozygous mice
Transcription profiling of P6 retinal endothelial cells (ECs) extracted from retinas wild_type and dll4 heterozygous mice
ORGANISM(S): Mus musculus 
2011-01-10 | E-MTAB-347 | biostudies-arrayexpress
TranscriptomicsA single cell transcriptome atlas of murine endothelial cells
The heterogeneity of endothelial cells (ECs), lining blood vessels, across tissues remains incompletely inventoried. We constructed an atlas of >32,000 single-EC transcriptomic data from 11 tissues of the model organism Mus musculus. We propose a new classification of EC phenotypes based on transcri...
ORGANISM(S): Mus musculus 
2020-02-13 | E-MTAB-8077 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of human sinusoidal endothelial cells, hepatocyte
We report the transcriptome human primary hepatocytes and liver sinusoidal endothelial cells. Hepatocytes were obtained from commercial sources. LSECs were isolated based on the coexpression of Tie2 and CD32b, te strategy of purification controlled by RNA-Seq. Comparison of the expression of the Ti...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-43984 | biostudies-arrayexpress
GenomicsAging-associated transcriptome changes in liver sinusoidal endothelial cells.
Aging-associated transcriptome changes in liver sinusoidal endothelial cells.
PRJNA894478 | ENA
TranscriptomicsVEGF-A stimulated gene expression in human liver sinusoidal endothelial cells
Transcriptomic analysis of VEGF-A stimulated liver sinusoidal endothelial cell gene expression. Untreated cells were compared to those treated with VEGF-A. VEGF-A stimulation is critical for normal LSEC phenotype, and the response to liver injury Two conditions: untreated vs. VEGF-A treated. LSEC...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-41110 | biostudies-arrayexpress
ProteomicsLiver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
Mild hemolysis of senescent erythrocytes occurs physiologically in the spleen resulting in Hb release, whereas pathologic erythrocyte rupture characterizes several diseases. Iron recycling from Hb and Hb detoxification have been attributed to the sequestration of Hb-haptoglobin complexes by macropha...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-12 | PXD051274 | Pride
Mouse Liver sinusoidal endothelial cells Hemoglobin clearance 
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