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Translation depnedent interactome of Hsp70 co chaperone Sis1 during heat shock.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-18 | PXD039134 | Pride
How heat shock inducesthe heat shock response (HSR) – a gene expression program encoding chaperones and other protein homeostasis (proteostasis) factors –remains an unresolved question in eukaryotic cell biology. Here we show that subcellular localization of the conserved J-protein Sis1 is a key reg...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-03-24 | PXD019170 | Pride
Sis1 potentiates the stress response to protein aggregation and elevated temperature
Proximity interactome labelling of Sis1 APEX2 during heat shock revealed its comprehensive interactome.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-18 | PXD039068 | Pride
Cells adapt to conditions that compromise protein conformational stability by activating various stress response pathways, but the mechanisms used in sensing misfolded proteins remain unclear. Moreover, aggregates of disease proteins often fail to induce a productive stress response. Here, using a y...
ORGANISM(S): Saccharomyces cerevisiae 
2020-10-25 | GSE151215 | GEO
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