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GenomicsGenome-wide Analysis of Chromatin Interactions in Human Cells
Millions of cis-regulatory sequences have recently been found in the human genome, but the function of most cis-elements are not yet clear, in part due to the difficulty in determining their regulatory targets, which are often located millions of base pairs away and separated by one or more unrelate...
ORGANISM(S): Homo sapiens 
2013-10-20 | E-GEOD-43070 | biostudies-arrayexpress
UnknownCharacterization of a newly discovered symbiont of the whitefly Bemisia tabaci (Hemiptera: Aleyrodidae).
Not available
S-EPMC3553764 | biostudies-literature
GenomicsA draft map of cis-regulatory sequences in the mouse genome [ChIP-Seq]
As the most widely used mammalian model organism, mice play a critical role in biomedical research for mechanistic study of human development and diseases. Today, functional sequences in the mouse genome are still poorly annotated a decade after its initial sequencing. We report here a map of nearl...
ORGANISM(S): Mus musculus 
2012-07-01 | E-GEOD-29218 | biostudies-arrayexpress
UnknownDiversity and evolution of the Wolbachia endosymbionts of Bemisia (Hemiptera: Aleyrodidae) whiteflies.
Not available
S-EPMC4113295 | biostudies-literature
ProteomicsPhotocatalytic proximity labeling technology for nanoparticle protein corona
We designed a photocatalytic proximity labeling technology for in situ labeling of corona proteins. When nanoparticles were exposed in plasma, they were immediately irradiated to induce the photocatalytic reaction, in which the inner Ce6 activated BP in the outer layer. BP was then released from nan...
ORGANISM(S): Mus Musculus 
2022-06-23 | PXD034930 |
ProteomicsDynamic analysis of nano-protein interaction in cell transport of nano-drugs based on proximity labeling strategy
We have constructed nanoparticles that can in-situ label the protein microenvironment in living cells. When the nanoparticles were exposed to cellular vesicles, hydrogen peroxide was used to initiate the labeling reaction for 1 minute. The nanoparticles could activate the biotin tag around them, and...
ORGANISM(S): Mus Musculus 
2023-07-12 | PXD043708 |
TranscriptomicsMorphological differentiation and secondary metabolism responses of Streptomyces coelicolor A3(2) to simulated microgravity based on comparative transcriptomics (2-color)
In order to gain a better understanding of the effects of Streptomyces coelicolor A3(2) wild type strain exposed to simulated microgravity condition by clinorotation, we constructed a whole genome microarray to screen simulated microgravity sensitive genes using the Agilent eArray 5.0 program. The g...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2014-02-01 | E-GEOD-53749 | biostudies-arrayexpress
ProteomicsMechanistic Insight into Glioma Through Spatially Multidimensional Proteomics
Characterizing the tumor microenvironment at the molecular level is essential for understanding the mechanisms of tumorigenesis and evolution. However, the specificity of the blood proteome in localized region of the tumor and its linkages with other systems is difficult to investigate. Here, we pro...
ORGANISM(S): Homo Sapiens 
2023-07-20 | PXD043970 |
ProteomicsGlobal phosphoproteomic analysis of mouse spermatocytes identified key kinases regulating meiosis
Protein phosphorylation, as one of the most important post-translational modifications, exerts crucial roles in regulating meiosis. However, there is a lack of systemic phosphoproteomic and functional analysis of phosphorylation in the meiosis of spermatocytes. To characterize the phosphorylation ev...
ORGANISM(S): Mus Musculus 
2022-03-07 | PXD032089 |
TranscriptomicsStress-dependent CHIP/Daxx interaction suppresses the p53 apoptotic program
Our previous studies have implicated CHIP as a co-chaperone/ubiquitin ligase, whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP (carboxyl terminus of Hsp70-interacting protein) and Daxx, death domain-...
ORGANISM(S): Mus musculus 
2010-04-03 | E-GEOD-14339 | biostudies-arrayexpress
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