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ProteomicsRadiation-induced bystander effect mediated by exosomes involves the replication stress in recipient cells
Exosomes secreted by irradiated cells mediate radiation-induced bystander effect, which is manifested by DNA breaks detected in recipient cells, yet the specific mechanism responsible for the generation of chromosome lesions remains unclear. In this study, naïve FaDu head and neck cancer cells were ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-31 | PXD032080 | Pride
Bystander effect Exosomes Mass spectrometry Q exactive plus Phosphoproteomics 
ProteomicsRadiation-induced bystander effect mediated by exosomes involves the replication stress in recipient cells.
Exosomes released by irradiated cells mediate radiation-induced bystander effect, which is manifested by DNA breaks detected in recipient cells, yet the specific mechanism responsible for generation of chromosome lesions remains unclear. In this study, naïve FaDu head and neck cancer cells were stim...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD032143 | Pride
Bystander effect  exosomes  ionizing radiation  non-targeted effects of radiation  replication stress 
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