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TranscriptomicsModeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data
Background. Most colorectal cancers (CRC) arise in a progression through adenoma to carcinoma phenotypes as a consequence of altered genetic information. Clinical progression of CRC may occur in parallel with distinctive signaling alterations. We designed multidirectional analyses integrating microa...
ORGANISM(S): Homo sapiens 
2010-08-01 | E-GEOD-20916 | biostudies-arrayexpress
GenomicsGenome wide extracellular signal-regulated kinase (ERK) pathway components interaction with human genome
Several recent studies, including ours, show that most components of signal transduction cascades including the extracellular signal-regulated protein kinase (ERK), that once were thought to act predominantly in cytoplasm, are in fact recruited to chromatin and are integral components of transcript...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-65323 | biostudies-arrayexpress
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