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Specific protein binders with high affinity, such as antibodies or nanobodies, are scarce for most solute carrier (SLCs) transporters. Moreover, general approaches that can systematically generate binders for multi-transmembrane proteins, such as SLCs, channels or GPCRs, are still missing. Purifying...
ORGANISM(S): Homo sapiens (Human) 
2024-06-17 | PXD046995 | Pride
Genome-wide association studies have identified >1000 loci associated with clinically important red blood cell (RBC) traits, such as hemoglobin content and cell volume. However, few of these associations have been characterized at the molecular level such that most causal genes and variants remain e...
ORGANISM(S): Homo sapiens 
2026-08-07 | GSE308629 | GEO
Pooled CRISPR screens identify genes and non-coding genomic regions that regulate red blood cell density
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