Slc30a10 - OmicsDI

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Professor Dept. Cell Biology 615 Michael Street Whitehead 446 Atlanta, GA, 30322 Emory University (1)
Victor Faundez MD, PhD Professor Dept. Cell Biology 615 Michael Street Whitehead 446 Atlanta, GA, 30322 Emory University (1)

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xref:PubMed:35921164 (1)
xref:PubMed:38285613 (1)
xref:PubMed:42167917 (1)
xref:PubMed:20028768 (1)
xref:PubMed:25582195 (1)
xref:PubMed:39596116 (1)

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AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice.

Not available

S-EPMC10933546 | biostudies-literature

Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity.

Not available

S-EPMC6877324 | biostudies-literature

Molecular mechanisms of SLC30A10-mediated manganese transport.

Not available

S-EPMC12480533 | biostudies-literature

Characterization of in vitro models of SLC30A10 deficiency.

Not available

S-EPMC8204349 | biostudies-literature

AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice

PRJNA1003945 | ENA

Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hypoxia-inducible factor signaling in mice

The essential metal manganese (Mn) induces neuromotor disease at elevated levels. The manganese efflux transporter SLC30A10 regulates brain Mn levels. Homozygous loss-of-function mutations in SLC30A10 induce hereditary Mn neurotoxicity in humans. Our prior characterization of Slc30a10 knockout mice ...

ORGANISM(S): Mus musculus

2024-02-09 | GSE247882 | GEO

NR4A1 is a HIF-dependent repressor of SLC30A10 transcription that controls manganese homeostasis.

Not available

S-EPMC12596596 | biostudies-literature

Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hypoxia-inducible factor signaling in mice

PRJNA1040862 | ENA

Bile acid composition regulates the manganese transporter Slc30a10 in intestine.

Not available

S-EPMC7458818 | biostudies-literature

Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retains manganese efflux activity.

Not available