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Seminal fluid can have wide-ranging effects on reproductive fitness – from affecting sperm fertilisation capacity and female reproductive physiology, to influencing offspring viability and health. Seminal fluid can also change in response to environmental conditions including diet, which of itself i...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-23 | PXD073093 | Pride
Protein kinase C epsilon (PKCe) has been shown to play a causative role in the generation of glucose intolerance and insulin resistance. Tissue-specific deletion of PKC indicates multiple sites of action, highlighting the kinase as a potential target for the treatment of type 2 diabetes. CIDD-015061...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-11 | PXD054895 | Pride
Transcriptional profiling was conducted on RNA from 8 xenograft L2987lung tumor tissue samples to identify genes affected by treatment with a VEGFR-2 small molecule inhibitor Experiment Overall Design: Baseline and 14 days post treatement gene expression profiling was performed using 8 xenograft L29...
ORGANISM(S): Mus musculus 
Epstein-Barr virus (EBV) is able to drive the transformation of B-cells, resulting in the generation of lymphocyte cell lines (LCLs) in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of BL31 ...
ORGANISM(S): Homo sapiens 
Axis specification in mouse is determined by a sequence of reciprocal interactions between embryonic and extra-embryonic tissues so that a few extra-embryonic genes appear as ‘patterning’ the embryo. Considering these interactions as essential, but lacking in most mammals the genetically driven appr...
ORGANISM(S): Bos taurus 
Mycobacterium avium subspecies paratuberculosis (MAP) infection is established following the ingestion of bacteria, their penetration of the intestinal mucosa and subsequent events of the host-parasite interaction. These bacteria invade M cells, macrophages and are capable of resisting host defenses...
ORGANISM(S): Bos taurus 
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