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TranscriptomicsSmall RNAs in Arabidopsis hybrid siliques
Five days post-fertilization siliques were collected for RNA extraction. After purification, small RNA libraries were generated for high throughput sequencing. Resulting sequences were analyzed to determine the contribution of the paternal genome to the small RNA transcriptome. Keywords: Epigenetic...
ORGANISM(S): Arabidopsis thaliana 
2009-03-24 | E-GEOD-15348 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human early stage non-small cell lung carcinoma to refine prognosis for adjuvant therapy
Abstract from paper - Potti A, et al Experiment Overall Design: Retrospective analysis of approximately 200 samples obtained from Duke, ACOSOG and CALGB to develop a Lung metagene predictor that would then be used to assess risk of recurrence and thus identify high risk patients with stage Ia non-sm...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3593 | biostudies-arrayexpress
TranscriptomicssRNA sequencing from wild-type Arabidopsis (diverse tissue types)
This set consists of small RNAs sequenced from wild-type Arabidopsis samples from multiple tissue types (floral, leaf, seedling, silique). Samples were prepared in two different labs and presumably under different (unknown) growth conditions, hence type A (UEA) and type B (University of Cambridge) s...
ORGANISM(S): Arabidopsis thaliana 
2012-01-10 | E-GEOD-31211 | biostudies-arrayexpress
TranscriptomicsHigh-throughput pyrosequencing of endogenous small RNAs from Arabidopsis thaliana wild-type and polIV mutants
Comparison of the endogenous small RNA content of Arabidopsis flower bud tissue: wild type vs. mutants in polIV pathways Keywords: High throughput 454 small RNA sequencing. Size fractionated small RNA from total RNA extracts was ligated to adapters, purified again and reverse transcribed. After PCR ...
ORGANISM(S): Arabidopsis thaliana 
2008-02-25 | E-GEOD-10180 | biostudies-arrayexpress
TranscriptomicsRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Recently, we defined four subtypes of pancreatic cancer that are associated with distinct histopathological characteristics and differential survival, namely, Squamous, Pancreatic Progenitor, Immunogenic, and ADEX (Bailey et al 2016, Nature). We also found that loss of CXCR2 was associated with a sw...
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-6620 | biostudies-arrayexpress
TranscriptomicsDifferential RISC association of endogenous human microRNAs predicts their inhibitory potential
It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) proteins, essential components of the RNA-induced silencing complex (RISC). However, recent data have suggested that the majority of mature miRNAs are not, in ...
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-58127 | biostudies-arrayexpress
TranscriptomicsThe viral and cellular microRNA targetome in lymphoblastoid cell lines
Epstein-Barr virus (EBV) is a human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-41437 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of tissues of Arabidopsis plants overexpressing artificial microRNAs vs wild_type and respective target gene mutants
Tissues of Arabidopsis plants overexpressing artificial microRNAs were compared to wild_type and respective target gene mutants (duplicate arrays)
ORGANISM(S): Arabidopsis thaliana 
2006-04-01 | E-TABM-63 | biostudies-arrayexpress
TranscriptomicsAge-dependent gene expression profiles after hepatic ischemia/reperfusion in mice
Experimental Design: 1. The goal of the experiment: Age-Dependent Gene Expression Profiles After Hepatic Ischemia/Reperfusion: Implications for the AP-1 and Ubiquitin-Proteosome Pathways 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surg...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10654 | biostudies-arrayexpress
TranscriptomicsDivergent genome expression profiles during hepatic ischemia in young and adult mice
Experimental Design: 1. The goal of the experiment: Age-Related Genome Expression Profiles During Hepatic Ischemia 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surgery, transplantation and shock and differs with age. In the present stu...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10652 | biostudies-arrayexpress
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