Small molecule activator

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CHEBI ID

CHEBI:16695 (7)
CHEBI:16750 (7)
CHEBI:16704 (7)
CHEBI:17345 (7)
CHEBI:17368 (7)
CHEBI:16708 (6)
CHEBI:16335 (6)
CHEBI:17568 (6)
CHEBI:16411 (6)
CHEBI:27897 (6)
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CHEBI:17256 (5)
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CHEBI:16040 (5)
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CHEBI:16742 (5)
CHEBI:25017 (5)
CHEBI:28044 (5)
CHEBI:17154 (5)
CHEBI:16393 (5)
CHEBI:16235 (5)
CHEBI:15940 (5)
CHEBI:27266 (5)
CHEBI:32816 (5)
CHEBI:30769 (5)
CHEBI:30754 (4)
CHEBI:17033 (4)

Metabolite Name

Hypoxanthine (6)
Adenosine (5)
Thiamine (4)
UMP (4)
Choline (4)
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Guanine (4)
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Guanosine (4)
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Classification

bacteria (2)

Study type

Transcription profiling by array (698)
ChIP-seq (294)
RNA-seq of coding RNA (105)
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ChIP-chip by array (38)
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Human - One-color microarray (2)
CLIP-seq (2)
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1999 (1)

Lab affiliation

Departments of Chemistry and Biological Sciences, Vanderbilt University (1)
Department of Biology University of Konstanz Germany (1)
Biozentrum LMU, Genetics Großhaderner Strasse 2-4 82152 Planegg-Martinsried phone +4989218074603 http://www.genetik.biologie.uni-muenchen.de/research/boshart/index.html (1)
Laboratory of Molecular Pharmacology and Drug Discovery, Institute of Chinese Materia Medica, The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518033, China (1)
Dr Georg E. Winter, Winter Lab, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria (1)
Director, Center for Proteomics and Bioinformatics Charles W. and Iona A. Mathias Professor of Cancer Research (1)
Department of Immunology and Microbiology, Scripps Research, USA (1)
Professor of Molecular Neurogenetics CIMR Deputy Director Cambridge Institute of Medical Research (CIMR) University of Cambridge (1)
Cancer Institute, University College London (1)
2Departments of Internal Medicine, University of Michigan, Ann Arbor MI 48109, USA. (1)
Northeastern University (1)
LAb of molecular bacteriology, Rega Institute, KU Leuven (1)
Department of Pharmacology and Lineberger Comprehensive Cancer Center at University of North Carolina at Chapel Hill (1)
Harvard Medical School (1)
University of Dundee (1)

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Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography

Our understanding of metabolic interactions between small symbiotic animals and bacteria or parasitic eukaryotes that reside within their bodies is extremely limited. This gap in knowledge originates from a methodological challenge, namely to connect histological changes in host tissues induced by b...

2021-07-06 | MTBLS2639 | MetaboLights

Apoptosis-inducing effects of aqueous extract of Eleutherococcus senticosus on non-small cell lung cancer cell proliferation

Non-small cell lung cancer is a malignant tumor with high morbidity and mortality worldwide. Eleutherococcus senticosus can induce apoptosis in non-small cell lung cancer cells, but the mechanism remains unclear. This study aimed to elucidate the role of Eleutherococcus senticosus in inducing apo...

2025-05-12 | MTBLS10545 | MetaboLights

A Small Molecule Activator of the TET2 Tumor Suppressor

PRJNA497516 | ENA

Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling

The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeostasis in response to oxidative stress by the regulation of multiple cytoprotective genes. Without stressors the activity of Nrf2 is inhibited by its interaction with the kelch-like ECH-associated protei...

ORGANISM(S): Mus musculus

2015-10-31 | E-GEOD-71695 | biostudies-arrayexpress

Small molecule TERT activator prevents aging and cognitive decline [ChIP-seq]

PRJNA966085 | ENA

Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction With the Small Molecule iKIX1

PRJNA299815 | ENA

Transcriptomic Profiling of Small Molecule Atf6 Modulators in the Retina

PRJNA1224216 | ENA

Phosphoproteomics Profiling of Non-Small Cell Lung Cancer Cells Treated with a Novel Phosphatase Activator

Activation of protein phosphatase 2A (PP2A) is a promising anti-cancer therapeutic strategy given this tumor suppressor’s ability to coordinately downregulate multiple pathways involved with growth and proliferation.Here, we studied the global signaling response signature of a novel small molecule a...

ORGANISM(S): Homo sapiens (Human)

2018-07-05 | PXD005698 | Pride

Discovery of Small Molecule Bak Activator for Lung Cancer Therapy.

Not available

S-EPMC8344021 | biostudies-literature

Direct observation of small molecule activator binding to single PR65 protein.

Not available

S-EPMC11738983 | biostudies-literature

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