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TranscriptomicsExpression data from breast cancer cell lines
Breast cancer is a genetically and phenotypically complex disease. To understand the role of microRNAs in this molecular complexity, we performed miRNA expression analysis in a cohort of molecularly well-characterized human breast cancer (BC) cell lines to discover miRNAs associated with the most co...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-41313 | biostudies-arrayexpress
TranscriptomicsTowards understanding breast cancer mechanisms to metastasize
How organ-specific metastatic traits accumulate in primary tumors remains unknown. We identified a role of the primary tumor stroma in selecting breast cancer cells that are primed for metastasis in the bone. A fibroblast-rich stroma in breast tumors creates a microenvironment that is similar to tha...
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-47389 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer Cell line Panel (OCCP): gene expression data.
Epithelial ovarian cancer is a very heterogeneous disease and remains the most lethal gynaecological malignancy in the Western world. Rational therapeutic approaches need to account for interpatient and intratumoral heterogeneity in treatment design. Detailed characterization of in vitro models repr...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-53418 | biostudies-arrayexpress
ProteomicsIntegrative analysis of genomics and proteomics data on clinical breast cancer tissue specimens extracted with acid guanidinium thiocyanate-phenol-chloroform
Acid guanidinium thiocyanate, phenol and chloroform extraction (AGPC) is a commonly used procedure to extract RNA from fresh frozen tissues and cell lines. In addition, DNA and proteins can be recovered, which makes AGPC an attractive source for integrative analysis on tissues of which little materi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080789 | MassIVE
TranscriptomicsMicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors (validation)
Liposarcomas are rare, heterogeneous and malignant tumors that can be divided into five histological subtypes with different characteristics and clinical behavior. Treatment consists of surgery in combination with systemic chemotherapy, but nevertheless mortality rates are high. More insight into th...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-45363 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors (discovery)
Liposarcomas are rare, heterogeneous and malignant tumors that can be divided into five histological subtypes with different characteristics and clinical behavior. Treatment consists of surgery in combination with systemic chemotherapy, but nevertheless mortality rates are high. More insight into th...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-45359 | biostudies-arrayexpress
GenomicsICGC breast cancer sequencing project SNP6 data
Affymetrix SNP6.0 breast cancer genome sequencing data
EGAD00010000915 | EGA
GenomicsEGAS00001000195-sc-20150416 - samples
We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.
EGAD00001001337 | EGA
GenomicsEGAS00001000042-sc-20150416 - samples
We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.
EGAD00001001334 | EGA
GenomicsBASIS_KOREAN_DATASET - samples
A comprehensive characterisation and analysis of human breast cancers through whole-genome sequencing.
EGAD00001001322 | EGA
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