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MetabolomicsInvestigation of the threonine metabolism of Echinococcus multilocularis: EmTDH as a potential drug target in alveolar echinococcosis
Alveolar echinococcosis is a severe zoonotic disease caused by the fox tapeworm E. multilocularis. New treatment options are urgently needed. Whole-organism-based screening allows the discovery of potential new anti-echinococcal compounds, but suffers from low- to medium-throughput. An alternative a...
2026-09-14 | MTBLS10738 | MetaboLights
MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS703 | MetaboLights
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
UnknownA Central Role for HLA-DR3 in Anti-Smith Antibody Responses and Glomerulonephritis in a Transgenic Mouse Model of Spontaneous Lupus.
Not available
S-EPMC5292932 | biostudies-literature
MetabolomicsSPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids
Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensit...
2017-02-14 | MTBLS427 | MetaboLights
MetabolomicsA shotgun metabolomics approach to characterize the dissolved organic matter pool in the Samail Ophiolite aquifer
The process of serpentinization has been implicated in supporting life on both early Earth and other worlds in our Solar System. While numerous studies have provided clues to the survival strategies of microbial communities in serpentinizing environments on modern Earth, characterizing microbial act...
2023-03-02 | MTBLS6081 | MetaboLights
UnknownAssociation of genetic liability to smoking initiation with e-cigarette use in young adults: A cohort study.
Not available
S-EPMC7971530 | biostudies-literature
UnknownThe prospective relationship between a-priori intentions for and patterns of e-cigarette use among adults who smoke cigarettes.
Not available
S-EPMC11589789 | biostudies-literature
MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS708 | MetaboLights
UnknownTranscriptome software results show significant variation among different commercial pipelines.
Not available
S-EPMC10623858 | biostudies-literature
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