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ModelsSmith2011_HumanHeartMitochondrian_MetabolicModel
This model is from the article: A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle. Smith AC, Robinson AJ. BMC Syst Biol. 2011 Jun 29;5(1):102. 21714867 , Abstract: ...
2005-01-01 | MODEL1106160000 | BioModels
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsA sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Myc is an oncogenic transcription factor frequently dysregulated in human cancer. To identify pathways supporting the Myc oncogenic program, we employed a genome-wide RNAi screen for Myc-synthetic-lethal (MySL) genes and uncovered a role for the SUMO-activating-enzyme (SAE1/2). Loss of SAE1/2 enzyma...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-34055 | biostudies-arrayexpress
UnknownRTOG 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation.
Not available
S-EPMC4334775 | biostudies-literature
GenomicsIdentification of Transcription Factor MEP-1::GFP Binding Regions in Embryos
modENCODE_submission_2600 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25800 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor PQM-1::GFP Binding Regions in L3
modENCODE_submission_2623 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25811 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung from wildtype and glucocorticoid recepter knockouts to investigate investigate the role of glucocorticoids in fetal lung development
The aim of this experiment is to investigate the role of glucocorticoids in fetal lung development in more detail.
ORGANISM(S): Mus musculus 
2007-05-31 | E-MEXP-861 | biostudies-arrayexpress
ProteomicsTargeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma
Synovial Sarcoma (SS) is driven by the SS18::SSX fusion oncoprotein and is ultimately refractory to therapeutic approaches. SS18::SSX alters ATP-dependent chromatin remodeling BAF (mammalian SWI/SNF) complexes, leading to the degradation of canonical (cBAF) complex and amplified presence of an SS18:...
ORGANISM(S): Homo sapiens (Human) 
2025-08-07 | PXD059936 | Pride
Synovial sarcoma  baf complexes  swi/snf  sumoylation  tak-981  subasumstat  dna damage  targeted therapy 
GenomicsIdentification of Transcription Factor SKN-1::GFP Binding Regions in L1
modENCODE_submission_2622 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25810 | biostudies-arrayexpress
MetabolomicsThe Effect of Dietary BIoactives on Gut Microbiome DivErsity (DIME) - A pilot study (Untargeted metabolomics)

The gut microbiome refers to the complex community of microorganisms (bacteria, fungi, archaea and viruses) present within our gut. The composition and complexity of gut microbiota communities are crucial for maintaining human health. Humans depend on the gut microbiota to undertake essential met...

2025-10-10 | MTBLS8100 | MetaboLights
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