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ModelsTran2009_CaDynamicsSERCA_Cardiac
This a model from the article: A thermodynamic model of the cardiac sarcoplasmic/endoplasmic Ca(2+) (SERCA) pump. Tran K, Smith NP, Loiselle DS, Crampin EJ. Biophys J 2009 Mar 4;96(5):2029-42 19254563 , Abstract: ...
2005-01-01 | MODEL1006230121 | BioModels
ModelsTran2009_CardiacActiveForceGeneration
This a model from the article: A metabolite-sensitive, thermodynamically constrained model of cardiac cross-bridge cycling: implications for force development during ischemia. Tran K, Smith NP, Loiselle DS, Crampin EJ. Biophys J 2010 Jan 20;98(2):267-7...
2005-01-01 | MODEL1006230116 | BioModels
MetabolomicsIntegrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma were characterized using multi-platform metabolic phenotyping with Nuclear Magnetic Resonance (NMR) spectroscopy and liquid chromatography-mass spectrometry (LC-MS). Quantitative mea...
2021-01-29 | MTBLS2014 | MetaboLights
UnknownSexual dimorphism, altered hippocampal glutamatergic neurotransmission, and cognitive impairment in APP knock-in mice.
Not available
S-EPMC11639043 | biostudies-literature
UnknownAntigen nature and complexity influence human antibody light chain usage and specificity.
Not available
S-EPMC4876604 | biostudies-literature
UnknownPhase 3 trial of first generation protease inhibitor therapy for hepatitis C virus/human immunodeficiency virus coinfection.
Not available
S-EPMC5295161 | biostudies-literature
TranscriptomicsA Phase Two Randomised Controlled Trial of Belimumab in Kidney Transplant Recipients Demonstrates Comparable Safety, a Reduction in De Novo Antibody Production and an Increase in Regulatory B Cells.
There is an urgent unmet need in solid organ transplantation for immunotherapeutic strategies that target B cells and plasma cells, ideally without increasing infectious complications. We conducted a phase 2 double-blind randomised placebo-controlled trial to assess the safety and potential efficacy...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-5906 | biostudies-arrayexpress
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
GenomicsEpigenome and transcriptome of naive pluripotent mouse embryonic stem (ES) cells cultured in 2i serum-free medium
This study describes the epigenetic and transcriptome profiling of mouse ES cells cultures in 2i serum-free medium. The proteins for which ChIP-Seq profiles were generated in these cells, as well as for cells grown in serum conditions, include H3K4me3, H3K36me3, H3K27me3, H3K9me3, Suz12 and Ezh2. A...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-23943 | biostudies-arrayexpress
UnknownA propensity score-matched, real-world comparison of ustekinumab vs vedolizumab as a second-line treatment for Crohn's disease. The Cross Pennine study II.
Not available
S-EPMC9305775 | biostudies-literature
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