Smokers - OmicsDI

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Organisms

Homo sapiens (523)
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Organisms

Homo sapiens (382)
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human lung metagenome (5)
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human metagenome (2)
Methanocaldococcus sp. 21A (1)
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Repository

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pride (28)
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Tissue

Lung (8)
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Heart (1)
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Primary cell (1)

Disease

Chronic obstructive pulmonary disease (5)
Non-small cell lung carcinoma (4)
Normal (2)
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Non-small cell lung cancer (1)
Head and neck cancer (1)
Head and neck cancer and chronic obstructive pulmonary disease (1)
Non-small cell lung cancer and chronic obstructive pulmonary disease (1)
Healthy (1)
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Emphysema (1)
Normal tissue (1)
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Obesity (1)
Digestive health in healthy adults at high risk of colorectal cancer (1)
Cervical cancer (1)
Carcinogenesis (1)
Age related macular degeneration (1)
Oral cavity cancer (1)
Oral squamous cell carcinoma (1)
Periodontitis (1)

Technology Type

Mass Spectrometry (28)
Shotgun proteomics (20)
Bottom-up proteomics (7)
Mass spectrometry (6)
Data-dependent acquisition (4)
Illumina HiSeq 2000 (3)
DiaPASEF (2)
HiSeq X Ten, ILLUMINA (1)
AB 5500 Genetic Analyzer, Ion Torrent PGM (1)
Illumina HiSeq 1000, Ion Torrent PGM, Illumina Genome Analyzer IIx (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Data-independent acquisition (1)

Instrument Platform

Affymetrix GeneChip(R) HT Scanner (8)
Affymetrix GeneChip Scanner 3000 7G (4)
Q Exactive (4)
General usage Laborartory equipment (2)
Lab Centrifuge (2)
Pegasus (2)
Illumina BeadScan (1)
Ion Torrent Proton (1)
NextSeq 550 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 3000 (1)
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Q Exactive HF (1)
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Xevo TQ MS (Waters) (1)
Direct infusion MS - (1)
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Xevo G2 QTOF (Waters) (1)
Bruker (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2014 (50)
2015 (47)
2012 (36)
2011 (31)
2017 (30)
2016 (30)
2025 (29)
2009 (28)
2024 (26)
2008 (26)
2019 (25)
2022 (24)
2013 (23)
2010 (23)
2026 (22)
2021 (22)
2020 (22)
2007 (15)
2023 (15)
2018 (15)
2006 (8)
2005 (3)
2004 (2)

CHEBI ID

CHEBI:17822 (3)
CHEBI:26271 (3)
CHEBI:16344 (3)
CHEBI:17126 (3)
CHEBI:29016 (3)
CHEBI:78646 (3)
CHEBI:25094 (3)
CHEBI:18237 (3)
CHEBI:16856 (3)
CHEBI:17929 (3)
CHEBI:17368 (3)
CHEBI:30769 (3)
CHEBI:75186 (2)
CHEBI:84741 (2)
CHEBI:84372 (2)
CHEBI:74450 (2)
CHEBI:28125 (2)
CHEBI:84829 (2)
CHEBI:15710 (2)
CHEBI:28997 (2)
CHEBI:21565 (2)
CHEBI:17768 (2)
CHEBI:40410 (2)
CHEBI:74965 (2)
CHEBI:72965 (2)
CHEBI:70959 (2)
CHEBI:70958 (2)
CHEBI:83360 (2)
CHEBI:83880 (2)
CHEBI:64549 (2)

Metabolite Name

N2-acetyllysine (2)
N6-acetyllysine (2)
Proline (2)
Glutamate (2)
FAD (2)
2-hydroxyglutarate (2)
2-aminoadipate (2)
Citrate (2)
NAD+ (2)
AMP (2)
CMP (2)
DCMP (2)
ADP (2)
Alpha-ketoglutarate (2)
Carnitine (2)
UMP (2)
Arginine (2)
Lysine (2)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – Sulphated and hydroxylated on C7H6N2O part (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) mtb (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – sulphated (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – sulphated (1)
C9H11NOS based mtb – coupled to C7H6N2O2 – sulphated (1)
C9H11NOS based mtb – coupled to C8H8N2O – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – glucuronidated – isomer II (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – glucuronidated – isomer I (1)
C9H11NOS based mtb – coupled to C8H10N2 – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H10N2 – sulphated (1)
Quinidine dihydroxylated Isomer II (1)

First Public Date

2014 (123)
2024 (52)
2025 (41)
2020 (38)
2022 (36)
2021 (35)
2023 (32)
2015 (30)
2019 (27)
2026 (26)
2018 (26)
2017 (23)
2013 (21)
2016 (9)

Study status

Completed (4)

Study type

Transcription profiling by array (153)
Methylation profiling by array (10)
Comparative genomic hybridization by array (5)
Unknown experiment type (4)
RNA-seq of coding RNA (4)
Interventional (4)
RNA-seq of non coding RNA (3)
Exome sequencing (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
Animal - One-color microarray (1)
Cell line - One-color microarray (1)
Human - One-color microarray (1)
ChIP-chip by array (1)
Transcription profiling by RT-PCR (1)
Other (1)
ChIP-seq (1)
MicroRNA profiling by array (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (1286)
2021 (1241)
2020 (1110)
2023 (1043)
2019 (984)
2025 (898)
2018 (830)
2024 (810)
2017 (701)
2016 (664)
2015 (565)
2014 (472)
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2011 (202)
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2008 (96)
2007 (44)
2006 (23)
2005 (20)
2004 (6)
2001 (4)
2000 (4)
2002 (2)
2003 (1)
1999 (1)
1997 (1)

Lab affiliation

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland (4)
Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland (3)
Institute of Bioinformatics, Bangalore, Karnataka, India (2)
1 - College of Pharmacy, University of Sharjah, Sharjah 2 - Sharjah Institute for Medical Research, University of Sharjah, Sharjah (1)
Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), University Road, Deralakatte, Mangalore 575018, India (1)
Core Facility Proteomics, Department of Clinical Chemistry, Universitry Medical Center Göttingen, Germany (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay (IITB), Powai, Mumbai, Maharashtra - 400076 (1)
Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Taoyuan, Taiwan (1)
Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel (1)
Federal University of Sao Paulo, Functional Proteomics Laboratory, Sao Jose dos Campos, Sao Paulo, Brazil. (1)
Institute of Bioinformatics 7th floor, Discoverer building, International Tech Park, Bangalore 560 066 (1)
Institute of Bioinformatics, Bangalore (1)
Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland (1)
McKusick-Nathans Institute of Genetic Medicine, Department of Biological Chemistry, Oncology and Pathology, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA (1)
Professor, Department of Pharmaceutical Sceicnes Washington State University Spokane, WA (1)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (1)
Section of Oral Health and Periodontology, Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden (1)
Sharjah Institute for Medical Research & Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates (1)
Tianjin Medical University Eye Hospital, Tianjin Medical University Ophthalmology Research Institute，Tianjin,300384 (1)
UC Davis Internal medicine (1)
Women's Health Integrated Research Center, Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA (1)

Location

Hong Kong (1)
Australia (1)
United Kingdom (1)
China (1)
France (1)

Keyword

Tocopherols (1)
Vitamin E (1)
Tocotrienols (1)
Alpha-Tocopherol (1)

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Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers (NMR assay)

A multiplatform comparison of serum of smokers (n=56) and non-smokers (n=57) using NMR spectroscopy and UPLC-MS was carried out to determine perturbed biochemical functions associated with tobacco smoking. This should be helpful for establishing causal relationships between exposure and adverse e...

2017-01-09 | MTBLS374 | MetaboLights

Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers (UPLC-MS assay)

2017-01-09 | MTBLS364 | MetaboLights

Gene expression in male and female smokers

Smoking is the second leading cause of preventable death in the United States. Cohort epidemiological studies have demonstrated that women are more vulnerable to cigarette-smoking induced diseases than their male counterparts, however, the molecular basis of these differences has been remained unkn...

ORGANISM(S): Homo sapiens

2015-05-01 | E-GEOD-47415 | biostudies-arrayexpress

Transcription profiling of human airway epithelium, large airways, from phenotypically normal smokers vs non-smokers

Upregulation of Expression of the Ubiquitin Carboxyl Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers; The microarray data deposited here is from 11 HG-U133A GeneChips, from 5 normal non-smokers and 6 phenotypic normal smokers, large airways. Samples from the small airways ...

ORGANISM(S): Homo sapiens

2009-04-25 | E-GEOD-5057 | biostudies-arrayexpress

Comparative genomic hybridization of human lung adenocarcinoma in never smokers

CGH array in Lung Adenocarcinoma in Never Smokers

ORGANISM(S): Homo sapiens

2010-12-31 | E-TABM-926 | biostudies-arrayexpress

Upregulation of Expression of Matrix Metalloproteinases in Alveolar Macrophages of HIV1+ Smokers with Early Emphysema

HIV1+ smokers develop emphysema at an earlier age and with a higher incidence than HIV1- smokers. Based on the knowledge that human alveolar macrophages (AM) are capable of producing proteases that degrade extracellular matrix components, we hypothesized that upregulation of AM matrix metalloprotein...

ORGANISM(S): Homo sapiens

2016-03-24 | E-GEOD-10038 | biostudies-arrayexpress

Decreased Expression of Intelectin 1 in The Human Airway Epithelium of Smokers Compared to Nonsmokers

Lectins are proteins present on cell surfaces or as shed extracellular proteins that function in innate immune defense as phagocytic receptors to recognize specific bacterial cell wall components. Based on the knowledge that cigarette smoking is associated with increased risk of bacterial infection,...

ORGANISM(S): Homo sapiens

2008-12-19 | E-GEOD-10006 | biostudies-arrayexpress

Transcription profiling of human airway epithelium, large airways, phenotypically normal smokers vs non-smokers, MAS5 (HuGeneFL)

Upregulation of Expression of the Ubiquitin Carboxyl Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers; The microarray data deposited here is from 44 HuGeneFL GeneChips, from 9 normal non-smokers and 13 phenotypic normal smokers, large airways, 2 samples per individual, one ...

ORGANISM(S): Homo sapiens

2008-11-07 | E-GEOD-5056 | biostudies-arrayexpress

Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD patients

Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases, and involves persistent airflow limitation and incorporates both emphysema and chronic bronchitis. Cigarette smoking has been identified as the main risk factor for disease development and progression. In a basi...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-10-21 | MSV000080275 | MassIVE

CIT - Homo sapiens - APUP - Genomic aberrations in Lung Adenocarcinoma in Never Smokers

41 lung adenocarcinoma from never-smokers hybridized on Illumina SNP arrays on 13 HumanCNV370-Quadv3 chips. High-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in 41 never smokers for identification of new minimal common regions (MCR) of gain or loss. The SNP arr...

ORGANISM(S): Homo sapiens

2011-07-28 | E-TABM-1169 | biostudies-arrayexpress

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