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In these experiments,HCT116 cells were subject to IP with anti-Smurf1 antibody or normal IgG antibody, and then followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2021-03-02 | PXD024476 |
Smurf1 modulates Smad signaling pathway in fibrotic cataract formation [mouse_ASC]
Smurf1 modulates Smad signaling pathway in fibrotic cataract formation [cell line]
Effects of Smurf1/2 on mouse ESC embryoid body formation and differentiation
Purpose: TGF-β/BMP signaling pathway has a significant role in fibrotic cataract. Smurf1, a ubiquitin protein ligase, regulates the TGF-β/BMP signaling pathway through the ubiquitin-proteasome system (UPS). This study aims to investigate the role of Smurf1 in the progression of fibrotic cataract and...
ORGANISM(S): Mus musculus 
2024-02-14 | GSE245411 | GEO
Purpose: TGF-β/BMP signaling pathway has a significant role in fibrotic cataract. Smurf1, a ubiquitin protein ligase, regulates the TGF-β/BMP signaling pathway through the ubiquitin-proteasome system (UPS). This study aims to investigate the role of Smurf1 in the progression of fibrotic cataract and...
ORGANISM(S): Homo sapiens 
2024-02-14 | GSE245407 | GEO
We aim to the investigate the role of SMURF1 in breast cancer progression. MCF-7 cells were used as the model and SMURF1 was silenced by siRNA.
ORGANISM(S): Homo sapiens 
2018-08-14 | GSE102653 | GEO
Effect of Smurf1 or Smurf2 deficiency on Gene Expression Profiling of aged mouse liver tissues
To examine the effects of Smurf1 and Smurf2 on embryonic stem cell (ESC) differentiation, we generated mouse ESC lines with Smurf2(flox/flox) (WT control) and Smurf1-/-;Smurf2(∆/∆) (DKO) allelles. These two lines were plated to form embryoid bodies (EBs). We found that Smurfs DKO EBs exhibit distinc...
ORGANISM(S): Mus musculus 
2026-09-28 | GSE202273 | GEO
Transcriptome analysis of RNAs extracted from livers of wild type or Smurf1 knock out (KO) or Smurf2 KO mice at age of 11 month old. We prepared RNA from the following groups: livers of Wild type (WT) or Smurf1 KO or Smurf2 KO mouse from mixed Black Swiss/129SvEv background at age of 11 month old. T...
ORGANISM(S): Mus musculus 
2018-12-19 | GSE113995 | GEO
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