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TranscriptomicsDifferential gene expression in mutants of Arabidopsis FAX1 compared to wild type
DNA microarray analysis (Affymetrix ATH1 GeneChip) on mutant lines of the gene At-FAX1 (At3g57280) in Arabidopsis thaliana was performed as described in Li et al. (2015). In total we analyzed the following comparisons: (A) flowers: fax1 knockout (n = 5) versus wild type (n = 5); (B) flowers: FAX1 ov...
ORGANISM(S): Arabidopsis thaliana 
2015-02-04 | E-MTAB-3090 | biostudies-arrayexpress
TranscriptomicsHepatic Transcriptional Profiling of Hatchling Chicks and Market-age Broiler Chickens during Fasting and Re-feeding
This study integrates global transcriptional profiling and the metabolic perturbation induced by fasting and re-feeding. Genetic control of growth and development should be revealed by systematic modeling of metabolic and regulatory pathways. Chicken oligo arrays were used for transcriptional profil...
ORGANISM(S): Gallus gallus 
2008-04-01 | E-GEOD-9745 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of bovine monocytes stimulated with with interferon-g and lipopolysaccharide for 2 or 16 hours to validate a bovine macrophage specific cDNA microarray
Background The response of macrophages to danger signals is an important early stage in the immune response. Our understanding of this complex event has been furthered by microarray analysis, which allows the simultaneous investigation of the expression of large numbers of genes. However, the mic...
ORGANISM(S): Bos indicus 
2006-09-20 | E-MAXD-16 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of abdominal adipose tissue in juvenile broiler chickens divergently selected for abdominal fatness or leanness
Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at SRA-INRA, France were used to profile abdominal adipose gene expression during juvenile development (1 to 11 weeks of age) and to identify differentially expressed genes...
ORGANISM(S): Gallus gallus 
2012-04-26 | E-GEOD-37585 | biostudies-arrayexpress
TranscriptomicsTcRBP40 pull-down ribonomics
RNA pull-down assay.
For the recombinant protein pull-down assays, 50 M-5g of recombinant His-tag TcRBP40 protein were bound to 100 uL of Ni-NTA resin (Qiagen) overnight at 4M-0C. 100 M-5g of total RNA from epimastigotes were incubated with the bound protein in 500 M-5l EMSA buffer at 4M-0C for 2...
ORGANISM(S): Trypanosoma cruzi 
2012-06-30 | E-MEXP-3057 | biostudies-arrayexpress
no omics definedHodgkin_IV-IIIB_Ben-Dov_CRG
Hodgkin lymphoma derived cell lines (from the Deutsche Sammlung von Mikroorganismen und Zellkulturen) were cultured in RPMI 1640 medium supplemented with

20% (HDML-2) or 10% (HD-MY-Z) heat inactivated fetal calf serum. Cytoplasmic RNA was extracted according to "Cytoplasmic_RNA_CRG" protocol...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-MEXP-2959 | biostudies-arrayexpress
TranscriptomicsHDAC Inhibitors induce tumor cell-selective pro-apoptotic transcriptional responses.
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes, coupled with biochemical studies demonstrating aberrant recruitment of epigenetic enzymes such as histone deacetylases (HDACs) and histone methyltransferases (HMTs) to promoter regions through association with on...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-43010 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression profiles of distinct human and mouse mammary epithelial cell types
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-02-20 | E-GEOD-67056 | biostudies-arrayexpress
TranscriptomicsBilberries reduce low-grade inflammation and subacute endotoxemia in individuals with features of metabolic syndrome - microarray/QPCR profiling of dietary effects of bilberries in PBMCs
Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. The most diverse source of dietary anti-inflammatory compounds is polyphenols and especially anthocyanins, which are major polyphenols in bilberries (Vaccinium myrtillus). We investigated the effec...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-34145 | biostudies-arrayexpress
MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
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