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TranscriptomicsExpression data in PD-L1 positive and PD-L1 negative human melanoma samples
Blocking the PD-1/PD-L1 immunosuppressive pathway has shown promise in the treatment of certain cancers including melanoma. This study investigates differences in the gene expression profiles of human melanomas that do or do not display the immunosuppressive protein PD-L1. Further understanding of g...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-65041 | biostudies-arrayexpress
UnknownUsing a sequential regimen to eliminate bacteria at sublethal antibiotic dosages.
Not available
S-EPMC4390231 | biostudies-literature
TranscriptomicsTranscription profiling time series of zebrafish hearts treated with dioxin (TCDD)
For analysis of gene expression changes in the zebrafish larvae heart in response to TCDD exposure, three replicate samples of heart tissue were collected at 73, 74, 76 and 84 hours post fertilization from larvae exposed to 1 ng/ml TCDD or vehicle from 72 - 73 hours post fertilization. For analysis ...
ORGANISM(S): Danio rerio 
2006-06-29 | E-MEXP-758 | biostudies-arrayexpress
UnknownComparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing.
Not available
S-EPMC3877988 | biostudies-literature
TranscriptomicsGlobal gene expression in catfish spleen after injection of lipopolysaccharide
A high-density oligonucleotide microarray for channel catfish (Ictalurus punctatus) was designed and produced with Maskless Array Synthesizer technology (MAS). The microarray contained ~379,652 24-mer oligonucleotides covering ~18,999 catfish unique sequences. The global expression profiling of the ...
ORGANISM(S): Ictalurus punctatus 
2005-11-30 | E-GEOD-3261 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 61 Salmonella enterica serovar Typhimurium isoltates to identify hotspots in genome variation and distinguish between different isolates from the same geographical region
A collection of 61 Salmonella enterica serovar Typhimurium (S. Typhimurium) of animal and human origin, matched as closely as possible by phage type, antimicrobial resistance pattern and place / time of isolation, and sourced from farms or hospitals in Scotland, were analysed by antimicrobial suscep...
ORGANISM(S): Salmonella enterica serotype Typhimurium 
2007-06-09 | E-SGRP-6 | biostudies-arrayexpress
TranscriptomicsEx vivo mouse model for hepatic schistosomiasis
An ex vivo approach to studying hepatic schistosomiasis used thick naive mouse liver sections and sterile culturing. This tissue is unfixed, unfrozen, and alive for subsequent in vitro studies. We have cultured and monitored these sections for up to 48 hrs noting unchanged gross hepato-cellular morp...
ORGANISM(S): Mus musculus 
2014-12-12 | E-GEOD-64071 | biostudies-arrayexpress
TranscriptomicsTranscriptional Responses of Schistosoma japonicum Exposed in vivo to Sub-Lethal Dosages of Praziquantel
We have used a Schistosoma japonicum infected murine model with in vivo sub-lethal dosages of praziquantel against adult parasites. Differential gene expression of parasites was followed between 30 minutes and 24 hours post- drug administration, using a whole transcriptome microarray platform. Diffe...
ORGANISM(S): Schistosoma japonicum 
2012-09-27 | E-GEOD-41149 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 4-week old Arabidopsis plants grown in soil flooded to the soil surface (root flooding) or completely submerged under 6 cm of water (submergence)
4-week old Arabidopsis plants grown in soil were flooded to the soil surface (root flooding) or completely submerged under 6 cm of water (submergence). Samples are collected at the time specified.
ORGANISM(S): Arabidopsis thaliana 
2013-01-30 | E-TIGR-120 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression by ileum enterocytes following treatment with probiotic Lactobacillus reuteri
Analysis of changes in gene expression when probiotics are in the neonatal mouse gut (4 hrs) and after they had been excreted (24 hrs post-gavage) Total RNA obtained from mouse ileum epithelial cells isolated by laser capture microdissection 4 or 24 hours after a single orogastric gavage with probio...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-26992 | biostudies-arrayexpress
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