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MetabolomicsMulti-omics analysis reveals microbiota-metabolite crosstalk in MASLD pathogenesis in a non-obese murine model

The rising global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), including its severe form metabolic dysfunction-associated steatohepatitis (MASH), underscores the urgency to elucidate its pathophysiology. To investigate key metabolic interactions central to MASLD...

2026-03-13 | MTBLS14048 | MetaboLights
TranscriptomicsRetroviral mutagenesis in haploid ES cells
Retroviral integration sites were mapped using inverse PCR to assess preferred integration sites of this virus in the genome after infection with the retrovirus and its impact on gene expression. Inverse PCR was applied on genomic DNA to identify retroviral integration sites. Inverse PCR allows to i...
ORGANISM(S): Mus musculus 
2011-10-25 | E-GEOD-33184 | biostudies-arrayexpress
TranscriptomicsSequencing of the non-ribosomal transcriptome allows the simultaneous identification of protein-coding and non-protein-coding RNAs
Deep Sequencing of protein-coding and non-protein-coding RNAs from mouse differentiated embryonic stem cells and 14.5dpc mouse fetal head Analysis of Ribominus RNA from mouse differentiated embryonic stem cells and 14.5dpc mouse fetal head There are no processed data files for GSM566806-GSM566811. ...
ORGANISM(S): Mus musculus 
2011-12-06 | E-GEOD-22959 | biostudies-arrayexpress
GenomicsThe B cell identity factor Pax5 regulates distinct transcriptional programs in early and late B lymphopoiesis
Pax5 controls the identity and development of B cells by repressing lineage-inappropriate genes and activating B-cell-specific genes. Here, we used genome-wide approaches to identify Pax5 target genes in pro-B and mature B cells. In these cell types, Pax5 bound to 40% of the cis- regulatory elements...
ORGANISM(S): Mus musculus 
2012-06-14 | E-GEOD-38046 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-sequencing of induced Neural Plate Border Stem Cells
We describe a so far uncharacterized, embryonic and self-renewing Neural Plate Border Stem Cell (NBSC) population with the capacity to differentiate into central nervous and neural crest lineages. NBSCs can be obtained by neural transcription factor-mediated reprogramming (BRN2, SOX2, KLF4 and ZIC3)...
ORGANISM(S): Homo sapiens 
2018-12-20 | E-MTAB-6911 | biostudies-arrayexpress
TranscriptomicsRNA Expression profiling of human induced Neural Plate Border Stem Cells, Neural Plate Border Stem Cell progeny and biological controls
We describe a so far uncharacterized, embryonic and self-renewing Neural Plate Border Stem Cell (NBSC) population with the capacity to differentiate into central nervous and neural crest lineages. NBSCs can be obtained by neural transcription factor-mediated reprogramming (BRN2, SOX2, KLF4, and ZIC3...
ORGANISM(S): Homo sapiens 
2018-12-20 | E-MTAB-5804 | biostudies-arrayexpress
UnknownThe UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains
Not available
S-SCDT-EMBOJ-2020-106094P | biostudies-other
UnknownModulating tumor immunity using advanced microbiome therapeutics producing an indole metabolite
Not available
S-SCDT-10_1038-S44319-025-00386-9 | biostudies-other
UnknownThe HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity
Not available
S-SCDT-EMM-2021-13952 | biostudies-other
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