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TranscriptomicsA549 Sagopilone
Anticancer drug sagopilone in lung cancer line A549. We performed gene expression analysis of lung cancer cell line A549 treated with sagopilone and paclitaxel. The aim was to analyse gene expression differences between the two drugs in two different concentrations. A549 cells were treated with medi...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-MTAB-377 | biostudies-arrayexpress
TranscriptomicsMyomgraft_Model_TASIP_2010_09
Human uterine fibroids are benign tumors derived from the smooth muscle layers of the uterus. Fibroid disease impacts up to 50% of premenopausal women in their daily life, and accounts for up to 50% of hysterectomies in the United States. Despite the health burden they impose, the development of the...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-MTAB-1882 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of xenografted tumors derived from human ovarian cell line model A2780 and its cisplatin resistant variant A2780cis
Molecular mechanisms underlying the development of resistance to platinum treatment in patients with ovarian cancer remain poorly understood. This is mainly due to the lack of appropriate in vivo models allowing identification of factors that are regulated during initial treatment and of acquired re...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-MTAB-1858 | biostudies-arrayexpress
TranscriptomicsPeritoneal endometriosis
We performed gene expression analysis human peritoneal endometriosis lesions, eutopic endometrium from endometriosis patients and peritoneum form endometriosis patients.The goal of the study was to analyse gene expression differences between peritoneal endometriosis lesion and eutopic endometrium an...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-MTAB-694 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of SH-SY5Y cells after treatment with soluble Abeta42_wt, Abeta42_G33A and Abeta40 for different timepoints
Although amyloid-beta42 (Abeta42) has long been implicated in the pathogenesis of Alzheimer disease (AD), the biological basis of its effects remains uncertain. Intraneuronal Abeta accumulation in brains of patients with AD or Down syndrome, in animal models, and in cultured cells has suggested an e...
ORGANISM(S): Homo sapiens 
2014-12-01 | E-MTAB-1841 | biostudies-arrayexpress
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