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GenomicsMechanism of Ikaros tumor suppression in Leukemia
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44218 | biostudies-arrayexpress
GenomicsMechanisms of Ikaros Tumor Suppression with HDAC1 through distinct histone markers in Pre-B ALL Leukemia
Ikaros functions as a master regulator of lymphocyte differentiation and a tumor suppressor. Ikaros binds DNA and regulates gene expression by chromatin remodeling. Mechanisms of Ikaros-mediated tumor suppression are unknown. Here we examined genome-wide occupancy of Ikaros and histone deacetylase 1...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44217 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in Nalm6 ALL leukemia cells
Identify the expression intensity for all genes in Nalm6 cells and all the genes are divided into 4 equal groups with group 1 containing the 25% of genes that were expressed at the highest levels, and group 4 containing the 25% of genes that were expressed at the lowest levels. Total RNA are isolate...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44214 | biostudies-arrayexpress
TranscriptomicssiRNA knockdown in human HEK293 cells transfected with siRNA specific for StarPap or PIPKIalpha or control siRNA
A loss of StarPap would be predicted to result in a decrease in cellular levels of mRNAs which it polyadenylates. Moreover, if PIPKIalpha has a function relationship with StarPap, knockdown of PIPKIalpha should cause a decrease in a pool of target mRNAs which require both StarPap and PIPKIalpha for...
ORGANISM(S): Homo sapiens 
2008-04-07 | E-GEOD-9361 | biostudies-arrayexpress
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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