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TranscriptomicsSingle-cell RNA-seq with Waterfall Reveals Molecular Cascades underlying Adult Hippocampal Neurogenesis
Somatic stem cells contribute to tissue ontogenesis, homeostasis, and regeneration through sequential processes. Systematic molecular analysis of stem cell behavior is challenging because classic approaches cannot resolve cellular heterogeneity or capture developmental dynamics. Here we provide a co...
ORGANISM(S): Mus musculus 
2015-08-30 | E-GEOD-71485 | biostudies-arrayexpress
TranscriptomicsGene expression after focal demyelination of the corpus callosum
To determine expression profiles of cytokines and growth factor profiles in the subventricular zone (SVZ) after demyelination we performed gene array analysis. In SVZ after 4 days post lesin (dpl) LPC-injected tissue, demonstrated regulation of BMP pathway elements, including increased chordin, nogg...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-21310 | biostudies-arrayexpress
UnknownIn vivo neutrophils hitchhiking for tumor targeting and microenvironment regulation boosts oncolytic virus therapy.
Not available
S-EPMC12490210 | biostudies-literature
ProteomicsRepurposing homoharringtonine for thyroid cancer therapy through TIMP1/FAK/PI3K/AKT signaling pathway
Homoharringtonine (HHT), an alkaloid isolated from Cephalotaxus, is an effective anti-leukemia agent that also exhibits inhibitory effects in various solid tumors. However, the impacts of HHT treatment on thyroid cancer (TC) remain unclear. This study aimed to explore whether HHT has anti-TC effects...
ORGANISM(S): Homo Sapiens 
2024-03-03 | PXD050295 |
ProteomicsProteomic investigations of transcription factors critical in geniposide-mediated suppression of alcoholic steatosis and in overdose induced hepatotoxicity on liver
Geniposide mediated therapeutic effects and overdose-induced hepatotoxicity
ORGANISM(S): Rattus Rattus 
2019-08-12 | PXD014996 |
TranscriptomicsTranscriptional dysregulation of synaptic genes in a human iPSC model of major mental disorders
Schizophrenia and other psychiatric disorders are postulated to be developmental disorders resulting from synapse dysfunction. How susceptibility genes for major mental disorders could lead to synaptic deficits in humans is not well-understood. Here we generated induced pluripotent stem cells (iPSCs...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-57821 | biostudies-arrayexpress
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