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GenomicsLdb1-nucleated transcription complexes function as primary mediators of erythroid gene activation
We used ChIP-Seq to map Ldb1, Scl and Gata1 binding sites in mouse total bone marrow cells. Together with functional studies comparing gene expression in Murine Erythroleukemia (MEL) cells expressing Ldb1 shRNA or control shRNA and bioinformatics analysis, we systematically determined the transcrip...
ORGANISM(S): Mus musculus 
2013-04-29 | E-GEOD-42843 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis reveals an activation of MHC-I and MHC-II pathways in chicken trachea immunized with infectious laryngotracheitis virus vaccine
Infectious laryngotracheitis (ILT) is an acute, contagious, upper respiratory disease, which is caused by gallid herpesvirus 1 (GaHV-1). Due to the mortality rates up to 70% depending on the virulence of the virus, it is of economic importance of the disease to explore the etiology of the ILT in the...
ORGANISM(S): Gallus gallus 
2014-04-08 | E-GEOD-46046 | biostudies-arrayexpress
GenomicsGenome-wide H3K4me3 analysis in Angus cattle with divergent tenderness
Tenderness is one of the most important properties of meat quality, which is influenced by genetic and environmental factors. As an intensively studied epigenetic marker, histone methylation, occurring on arginine and lysine residues, has pivotal regulatory functions on gene expression. To examine w...
ORGANISM(S): Bos taurus 
2015-03-31 | E-GEOD-61936 | biostudies-arrayexpress
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