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ProteomicsThe disturbance of lipid metabolism by the TNF-α /PLEKHA5/FCRLA axis leads to the proliferation, invasion and metastasis of cutaneous malignant melanoma
Background: Cutaneous malignant melanoma (CMM) is one of the most highly fatal cancers; its pathogenesis requires study. We recognize that abnormalities in lipid metabolism may be associated with the risk of CMM development; nevertheless, the role of lipid metabolism in the proliferation, invasion, ...
ORGANISM(S): Homo Sapiens 
2024-08-12 | PXD054835 |
UnknownLipoprotein (a) Testing in Patients With Atherosclerotic Cardiovascular Disease in 5 Large US Health Systems.
Not available
S-EPMC11935684 | biostudies-literature
UnknownGenome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation.
Not available
S-EPMC7768758 | biostudies-literature
Genomicsena-DATASET-BGI-31-12-2014-03:23:33:590-567 - samples
Gastric Cancer (GC) is a highly heterogeneous disease. To identify potential clinically actionable therapeutic targets that may inform individualized treatment strategies, we performed whole-exome sequencing on 78 GCs of differing histologies and anatomic locations, as well as whole-genome sequencin...
EGAD00001001118 | EGA
GenomicsWGS and WES of 78 pairs Chinese gastric cancer
Gastric Cancer (GC) is a highly heterogeneous disease. To identify potential clinically actionable therapeutic targets that may inform individualized treatment strategies, we performed whole-exome sequencing on 78 GCs of differing histologies and anatomic locations, as well as whole-genome sequencin...
EGAS00001001056 | EGA
Genomics5-hydroxymethylcytosine-mediated epigenetic modifications between iPSCs and hESCs
Mammalian somatic cells can be directly reprogrammed into induced pluripotent stem cells (iPSCs) by introducing defined sets of transcription factors. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem (ES) cells. Human ES ...
ORGANISM(S): Homo sapiens 
2013-03-21 | E-GEOD-37050 | biostudies-arrayexpress
ProteomicsMetabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
Metabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032290 |
UnknownDisturbed Flow Induces Reprogramming of Endothelial Cells to Immune-like and Foam Cells under Hypercholesterolemia during Atherogenesis.
Not available
S-EPMC11908347 | biostudies-literature
GenomicsFacilitates chromatin transcription complex is a marker and target of aggressive cancers with lower survival rates
The Facilitates Chromatin Transcription (FACT) is involved in chromatin remodeling during transcription, replication and DNA repair and is considered to be an ubiquitously expressed complex that has no known associations with any disease. However, we discovered that FACT is expressed in very limited...
ORGANISM(S): Homo sapiens 
2013-03-22 | E-GEOD-45393 | biostudies-arrayexpress
ProteomicsProtective mechanisms of heparin against AGEs-induced endothelial injury
Advanced glycation end products (AGEs) in diabetes can cause endothelial damage. Heparin, widely known as a recognized anticoagulant, is also a multifunctional therapeutic drug. This study investigated whether heparin could ameliorate AGEs-induced endothelial injury. Remarkably, heparin effectively ...
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD056219 |
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