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MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
TranscriptomicsDGE analysis of transcriptome change during photoperiodic regulation of potato tuber formation
We analyzed the transcriptome change during photoperiodic regulation of potato tuber formation 3 samples from longday condition and 2 samples from shortday condition were sequenced
ORGANISM(S): Solanum tuberosum 
2014-03-20 | E-GEOD-45008 | biostudies-arrayexpress
UnknownThe impact of sarcopenia on prognosis and fruquintinib efficacy in advanced colorectal cancer: a retrospective and mendelian randomization study.
Not available
S-EPMC12307208 | biostudies-literature
ProteomicsLibrary-Based, Multiplexed Strategy for Mapping Protein Interaction Networks via Crosslinking
Protein-protein interactions are fundamental to cellular function, yet resolving their interaction interfaces and dynamic behaviors in native biological contexts remains challenging, particularly for weak or transient interactions. Crosslinking strategies based on noncanonical amino acids offer an e...
ORGANISM(S): Homo Sapiens 
2026-02-28 | PXD075032 |
ProteomicsSelf-priming of Plk1 binding to BubR1 ensures accurate mitotic progression
Plk1 is a key mitotic kinase that localizes to distinct subcellular structures to promote accurate mitotic progression. Plk1 recruitment depends on direct interaction between polo-box domain (PBD) on Plk1 and PBD binding motif (PBD BM) on the interactors. However, recent study showed that PBD BM alo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096264 | MassIVE
ProteomicsProteomic and transcriptome analysis of DIA protein in Morchella edulis
In proteomics, DIA technology, as a high-throughput and high-sensitivity protein detection technique, can comprehensively and accurately identify and quantify proteins in samples. For morel mushrooms, DIA proteomic analysis can provide a deeper understanding of their protein composition, structure, ...
ORGANISM(S): Morchella Sextelata 
2024-11-25 | PXD058217 |
ProteomicsNovel molecular glue degraders against broad range of myeloma and lymphoma cancer cell lines
Targeted protein degradation of neosubstrates plays a crucial role in treating hematological cancers with IMiDs therapy. However, the inevitable drug resistance and hematological toxicities remain persistent challenges, limiting their clinical efficacy. Herein, we present the discovery of a lead deg...
ORGANISM(S): Homo Sapiens 
PXD053334 |
ProteomicsIdentification of African Swine Fever Virus pS273R (ASFV pS273R) interacting proteins in the cell lysates prepared from the Porcine alveolar macrophages (PAMs) cells by immunoprecipitation coupled with mass spectrometry analysis
Identification of pS273R interacting proteins in cell lysates of PAM cells
ORGANISM(S): Sus Scrofa 
PXD028692 |
ProteomicsUrinary Proteomic Characteristics of Hyperuricemia and Their Possible Links with the Occurrence of Hyperlipidemia and Type 2 Diabetes Mellitus
We performed label-free liquid chromatography MS/MS spectrometry analysis of urine samples from 26 HUA patients and 25 healthy controls, attempting to establish the possible protein links between hyperuricemia and these diseases by profiling urine proteome.
ORGANISM(S): Homo Sapiens 
2019-12-24 | PXD016900 |
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
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