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MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
UnknownCharacterization of ciprofloxacin-resistant and ESBL-producing Salmonella enteric serotype Derby in Eastern China.
Not available
S-EPMC6423743 | biostudies-literature
MetabolomicsPFKFB3-mediated glycolysis boosts fibroblast activation and subsequent kidney fibrosis

Renal fibrosis, a hallmark of chronic kidney diseases, is driven by the activation of renal fibroblasts. Recent studies have highlighted the role of glycolysis in this process. Nevertheless, one critical glycolytic activator, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3), remain...

2024-03-12 | MTBLS8281 | MetaboLights
ProteomicsWanxi White Goose testis proteomics
The testicular tissue of Wanxi white geese was selected from three stages of the laying cycle (initial, peak and end stages), and the DIA strategy was used for proteomic sequencing.
ORGANISM(S): Anser Cygnoides 
2024-04-02 | PXD051168 |
ProteomicsHungarian white goose testis proteomics
The testicular tissue of Hungarian White Goose was selected from three stages of the laying cycle (initial, peak and end stages), and the DIA strategy was used for proteomic sequencing.
ORGANISM(S): Anser Cygnoides 
2024-04-03 | PXD051163 |
ProteomicsHuman HNF1A KI mice liver proteome analysis
Nonalcoholic fatty liver disease (NAFLD) is a pathological condition caused by excessive fat accumulation in liver. HNF1A is the pathogenic cause of hepatocellular adenoma and HCC. It is an important transcription factor in liver. We constructed a knock-in mice expressing a human dominant negative H...
ORGANISM(S): Mus Musculus 
2023-03-02 | PXD040561 |
ProteomicsQuantitative Proteome Profiling of Maize Root zones Provides Insight into the Proteins Associated with Enhance Water Uptake in Maize
In order to get a better understanding of protein functions related to water uptake in maize, we investigated the proteome dynamics of cv. Anyu308 root system at three key zones divided into Upper root (0cm-20cm), Middle root (20cm-40cm), and Lower root (40cm-60cm) by label-free quantitative shotgun...
ORGANISM(S): Zea Mays 
2021-05-26 | PXD026269 |
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