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TranscriptomicsBreast tumors
Additional experiments used for intrinsic gene selection. Sorlie et al. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74. This Series accompanies Series GSE4335. Experiments that were used to make the "intrinsic" gene list from. Set of arrays organized by shared biological context, su...
ORGANISM(S): Homo sapiens 
2006-03-06 | E-GEOD-4336 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of breast tumors to identify links between copy number alterations and specific clinicopathological parameter
Breast cancer is a leading cause of cancer-death among women, where the clinicopathological features of tumors are used to prognosticate and guide therapy. DNA copy number alterations (CNAs), which occur frequently in breast cancer and define key pathogenetic events, are also potentially useful prog...
ORGANISM(S): Homo sapiens 
2006-12-01 | E-SMDB-3878 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast tumor subtypes
Experiments that were used to make the "intrinsic" gene list from.
ORGANISM(S): Homo sapiens 
2005-10-13 | E-SMDB-2227 | biostudies-arrayexpress
TranscriptomicsMicrometastasis primary tumors
Primary tumors from a series of breast cancer patients evaluated for the presence of tumor cells in bone marrow. Samples were taken at primary surgery, RNA isolated from fresh frozen tumors, amplified and hybridized to 42k cDNA arrays. Set of arrays organized by shared biological context, such as or...
ORGANISM(S): Homo sapiens 
2007-08-12 | E-GEOD-3985 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast carcinoma tissues representing 930 patients with 17.4 years mean follow-up, basal cytokeratin expression was associated with decreased disease-specific survival
Expression profiling studies have classified breast carcinomas into luminal, normal breast-like, HER2 expressing and basal-like groups, with the latter two associated with poor outcomes. This study's objectives were to define an immunohistochemical profile that identifies basal-like tumors, to ident...
ORGANISM(S): Homo sapiens 
2006-09-15 | E-SMDB-2863 | biostudies-arrayexpress
TranscriptomicsSubtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
The VEGF targeted antiangiogenic drug bevacizumab has shown varying results in clinical trials of breast cancer. Identifying robust biomarkers for selecting patients that may benefit from bevacizumab treatment and for monitoring of response is important for the future use of this drug. Two establish...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-37543 | biostudies-arrayexpress
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