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GenomicsK. lactis Ste12-myc ChIP-Seq in pheromone-responding a cells
The purpose of this experiment was to determine the genes directly regulated by Ste12 in K. lactis. The experiment was performed in a cells to determine if the a-specific genes were bound by Ste12. Ste12 was tagged with c-myc and was immunoprecipitated with a c-myc antibody. Cells were starved in SD...
ORGANISM(S): Kluyveromyces lactis 
2015-07-06 | E-GEOD-65792 | biostudies-arrayexpress
TranscriptomicsGene expression arrays comparing Kluyveromyces lactis wild-type a cells to MATa2 knock-out a cells and wild-type alpha cells to MATalpha2 knock-out alpha cells
We examine how different transcriptional network structures can evolve from a common, ancestral network. We show that regulatory protein modularity, conversion of one cis-regulatory sequence to another, distribution of binding energy among protein-protein and protein-DNA interactions, and exploitati...
ORGANISM(S): Kluyveromyces lactis 
2012-06-29 | E-GEOD-39027 | biostudies-arrayexpress
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