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TranscriptomicsBM clonal evolution in Fanconi anemia patients
Arrays-CGH and/or SNP-array data from n=57 Fanconi anemia BM and n=36 paired fibroblasts
ORGANISM(S): Homo sapiens 
2011-07-28 | E-MTAB-529 | biostudies-arrayexpress
TranscriptomicsGenomic profiling by array-CGH/SNP of paired xenograft and diagnosis T-cell Acute Lymphoblastic Leukemia (T-ALL) samples.
Arrays-CGH and/or SNP-array data from n=25 patients with T-ALL, including diagnosis, xenografted, remission and/or relapse samples (total 62 samples).
ORGANISM(S): Homo sapiens 
2011-03-23 | E-MTAB-593 | biostudies-arrayexpress
TranscriptomicsN-Me duplication in T-cell acute lymphoblastic leukemia cases
Arrays-CGH data from n=8 T-cell acute lymphoblastic leukemia
ORGANISM(S): Homo sapiens 
2014-09-07 | E-MTAB-2775 | biostudies-arrayexpress
UnknownThe use of 4,4,4-trifluorothreonine to stabilize extended peptide structures and mimic β-strands.
Not available
S-EPMC5753055 | biostudies-literature
TranscriptomicsGene expression signatures of 64 T-ALL patient diagnosis samples
Genetic studies have shown that human T-ALLs can be divided into subgroups that are characterized by unique gene expression signatures and relate to stages of T-cell differentiation at which the leukemic cells arrest. Each molecular subgroup has characteristic genetic abnormalities that cause aberra...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-62156 | biostudies-arrayexpress
UnknownA Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.
Not available
S-EPMC5481742 | biostudies-literature
UnknownEvaluation of a novel therapeutic education programme for people with alcohol use disorder in France: a mixed-methods intervention study protocol (ETHER).
Not available
S-EPMC8751002 | biostudies-literature
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for 64 T-ALL patient samples
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61866 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures of 64 T-ALL patient samples
The T-cell leukemia homeobox 1 (TLX1, HOX11) transcription factor is critically involved in the multistep pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) and often cooperates with NOTCH1 activation during malignant T-cell transformation. However, the exact molecular mechanisms by which t...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-62131 | biostudies-arrayexpress
UnknownA novel tumor suppressor function of Kindlin-3 in solid cancer.
Not available
S-EPMC4253411 | biostudies-literature
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