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Fibroblast growth factor 2 (FGF2) is well known as a promoter of cell proliferation, however, in some cellular contexts, it can induce cell cycle arrest or cell death. In Y1 murine adrenocortical carcinoma cell line, FGF2 induces G0/G1 transition but delays S-phase progression and permanently block ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-10-23 | MSV000081638 | MassIVE
WKY and LEW strains have been widely studied for their differential susceptibility to experimental glomerulonephritis. In particular these strains show strong variations in the macrophage activation. This dataset measures expression of macrophages in backcross population of WKY DC and LEW rats and ...
ORGANISM(S): Rattus norvegicus 

Characterizing the mode of action of antimalarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to inform on the mechanism of action of antimalarial leads ...

2023-09-27 | MTBLS6580 | MetaboLights
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