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TranscriptomicsOverexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity
Aims/hypothesis: While lipid deposition in skeletal muscle is considered to be involved in obesity-associated insulin resistance, neutral intramyocellular lipid (IMCL) accumulation per se does not necessarily induce insulin resistance. We previously demonstrated that overexpression of the lipid drop...
ORGANISM(S): Rattus norvegicus 
2013-01-29 | E-GEOD-43832 | biostudies-arrayexpress
TranscriptomicsMYB36 regulates the transition from proliferation to differentiation in the Arabidopsis root
Stem cells are defined by their ability to self-renew and produce daughter cells that proliferate and mature. These maturing cells transition from a proliferative state to a terminal state through the process of differentiation. In the Arabidopsis thaliana root the transcription factors SCARECROW an...
ORGANISM(S): Arabidopsis thaliana 
2015-07-20 | E-GEOD-70584 | biostudies-arrayexpress
TranscriptomicsImmortalized clonal brown, beige and white adipose cell lines
Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1-positive cells that emerge in white fat from a non...
ORGANISM(S): Mus musculus 
2012-07-23 | E-GEOD-39562 | biostudies-arrayexpress
UnknownEvidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.
Not available
S-EPMC4375076 | biostudies-literature
UnknownSynthesizing scientific literature with retrieval-augmented language models.
Not available
S-EPMC12935541 | biostudies-literature
UnknownAssessing the potential fire tolerance of conifer saplings in cold and wet environments using a pyro-ecophysiology approach.
Not available
S-EPMC12894159 | biostudies-literature
UnknownReduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes.
Not available
S-EPMC4023412 | biostudies-literature
UnknownBeige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Not available
S-EPMC3402601 | biostudies-literature
UnknownCombined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition.
Not available
S-EPMC12645172 | biostudies-literature
UnknownA phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy.
Not available
S-EPMC5664308 | biostudies-literature
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