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TranscriptomicsOverexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity
Aims/hypothesis: While lipid deposition in skeletal muscle is considered to be involved in obesity-associated insulin resistance, neutral intramyocellular lipid (IMCL) accumulation per se does not necessarily induce insulin resistance. We previously demonstrated that overexpression of the lipid drop...
ORGANISM(S): Rattus norvegicus 
2013-01-29 | E-GEOD-43832 | biostudies-arrayexpress
TranscriptomicsImmortalized clonal brown, beige and white adipose cell lines
Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1-positive cells that emerge in white fat from a non...
ORGANISM(S): Mus musculus 
2012-07-23 | E-GEOD-39562 | biostudies-arrayexpress
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