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UnknownAutoantibody signatures involving glycolysis and splicesome proteins precede a diagnosis of breast cancer among postmenopausal women.
Not available
S-EPMC4085738 | biostudies-literature
TranscriptomicsRNA sequencing of C57BL/6J mice, heterozygous for knockout of Hnrnph1 gene, as well as C57BL/6J mice controls
Previous studies of congenic lines of C57BL/6J-DBA/2J mice compared to C57BL/6 mice revealed a 0.23 QTL for sensitivity to methamphetamine on chromosome 11, which contains two protein coding genes, Rufy1 and Hnrnph1. Subsequent transcription activator-like effector nucleases (TALENs)-mediated introd...
ORGANISM(S): Mus musculus 
2017-02-01 | GSE76929 | GEO
UnknownA conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Not available
S-EPMC3703396 | biostudies-literature
UnknownGenome-wide analysis of alternative splicing differences in hepatic ischemia reperfusion injury.
Not available
S-EPMC11682299 | biostudies-literature
TranscriptomicsMis-splicing of Mdm2 leads to Increased P53-Activity and Craniofacial Defects in a MFDM Eftud2 Mutant Mouse Model
Purpose: EFTUD2, a GTPase and core component of the splicesome, is known to be mutated in patients with mandibulofacial dysostosis with microcephaly (MFDM). In this study, we examine the role of this gene in neural crest cells, the precursors of bones and cartilages affected in MFDM patients. Method...
ORGANISM(S): Mus musculus 
2021-09-03 | GSE157356 | GEO
UnknownGenomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations.
Not available
S-EPMC5323170 | biostudies-literature
UnknownTMT-Based Quantitative Proteomic Analysis Reveals the Crucial Biological Pathways Involved in Self-Incompatibility Responses in Camellia oleifera.
Not available
S-EPMC7139391 | biostudies-literature
UnknownGenome-wide identification and functional prediction of novel and fungi-responsive lincRNAs in Triticum aestivum.
Not available
S-EPMC4791882 | biostudies-literature
UnknownCoinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34+ cells via inhibition of senescence.
Not available
S-EPMC7695631 | biostudies-literature
GenomicsSystematic Identification and Characterization of Long Non-coding RNAs in Mouse Mature Sperm
Increasingly, studies have shown that mature spermatozoa contain many transcripts including mRNAs and miRNAs. However, the expression profile of long noncoding RNAs (lncRNAs) in mammalian sperm has not been systematically investigated. Here, we used highly purified RNA to investigate lncRNA expressi...
ORGANISM(S): Mus musculus 
2017-02-04 | GSE88732 | GEO
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