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TranscriptomicsGenome-wide survey of large rare copy number variations in Alzheimer’s disease among Caribbean Hispanics
Recently genome-wide association studies have identified significant association between Alzheimer’s disease and variations in CLU, PICALM, BIN1, CR1, MS4A4/MS4A6E, CD2AP, CD33, EPHA1 and ABCA7. However, the pathogenic variants in these loci have not yet been found. We conducted a genome-wide scan f...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-33528 | biostudies-arrayexpress
GenomicGenADA/LONG/Imaging (Genetic Alzheimer's Disease Associations)

GenADA is a multi-site collaborative study, involving GlaxoSmithKline Inc and nine medical centres in Canada, to develop a dataset containing 1000 Alzheimer's disease patients and 1000 ethnically-matched controls in order to associate DNA sequence (allelic) variations in candidate genes w...

phs000219 | dbGaP
TranscriptomicsMisprocessing of APP and accumulation of β-Amyloid causes early alteration of pathways implicated in late-onset Alzheimer disease.
Genome-wide association studies (GWAS) have identified genes in lipid metabolism,inflammation and vesicular trafficking pathways as risk factors for late onset Alzheimer disease (LOAD). The mechanism by which they cause AD and their relationship to the amyloid cascade affected by genes causing early...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-31372 | biostudies-arrayexpress
UnknownGenetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Not available
S-EPMC6463297 | biostudies-literature
UnknownExtracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors.
Not available
S-EPMC10962646 | biostudies-literature
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