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MetabolomicsAn ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants

BACKGROUND: Stool metabolites provide essential insights into the function of the gut microbiome. The current gold standard for storage of stool samples for metabolomics is flash-freezing at - 80 °C which can be inconvenient and expensive. Ambient temperature storage of stool is ...

2021-01-27 | MTBLS201 | MetaboLights
MetabolomicsCoupled nitrogen fixation and substrate stabilization drive ecological strategy shifts during microbial succession

Background:

Primary succession is predicted to proceed through shifts from stress-tolerant to competitive to cooperative ecological strategies as resource availability increases, yet molecular evidence for these transitions in microbial systems remains limited. Here, we used an integrated m...

2026-03-12 | MTBLS14041 | MetaboLights
MetabolomicsDiscovery of novel metabolic pathways and regulatory mechanisms of ammonia-oxidizing bacteria in organic materials stabilization

Background Ammonia-oxidizing bacteria (AOB) play a crucial role in the microbiome of the global nitrogen cycle. Yet, their regulatory functions in the metabolic pathways involved in organic material stabilization (OMS) are not fully understood. We employed...

2025-10-23 | MTBLS13207 | MetaboLights
TranscriptomicsThe Rpd3 Core Complex is a Chromatin Stabilization Module
The S. cerevisiae Rpd3 large (Rpd3L) and small (Rpd3S) histone deacetylase (HDAC) complexes are prototypes for understanding transcriptional repression in eukaryotes [1]. The current view is that they function by deacetylating chromatin, thereby limiting accessibility of transcriptional factors to t...
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-01 | E-GEOD-33829 | biostudies-arrayexpress
TranscriptomicsStabilization competency signature
Comparison of gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture required for successful reprogramming mRNA profilling 4 SI clones at 5 time points, 4 SC clones at 6 time points, and 3 feeder samples.
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-42100 | biostudies-arrayexpress
TranscriptomicsStabilization of ß-catenin during murine Kidney Development
We define a pathogenic role for a ß-catenin-activated genetic pathway in murine renal dysplasia. Cre-mediated stabilization of ß-catenin in the ureteric cell lineage prior to the onset of kidney development increased ß-catenin levels and caused renal aplasia or severe hypodysplasia. A genome-wide an...
ORGANISM(S): Mus musculus 
2011-03-28 | E-GEOD-20325 | biostudies-arrayexpress
ProteomicsAPC/CCdc20 dependent degradation of Clb4 is all there is to astral microtubule stabilization
Coordination between sister chromatid separation and segregation is crucial for accurate chromosome partitioning to the offspring. Key to this process is the ability of mitotic spindle microtubules to respond to different molecular signals and remodel their dynamics accordingly. Based on their funct...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-19 | PXD028828 | Pride
Astral microtubule stabilization 
GenomicsMicrobial communities in Waste Stabilization Ponds, Egypt
Microbial communities in Waste Stabilization Ponds, Egypt Metagenome
PRJNA1484938 | ENA
GenomicsG-quadruplex stabilization
The effect of prolonged G-quadruplex stabilization on the functions of human cells
PRJEB85998 | ENA
TranscriptomicsTranscription profiling of human adipose Tissue during Weight Loss
We investigated the regulation of adipose tissue (AT) gene expression during different phases of a dietary weight loss program and its relationship with insulin sensitivity. Obese women followed a weight reduction program composed of an energy restriction phase (ER) with a 4-week very-low-calorie di...
ORGANISM(S): Homo sapiens 
2009-05-16 | E-GEOD-11975 | biostudies-arrayexpress
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