Sort   by:  
 Page size 
TranscriptomicsRole of ICOS:ICOSL interaction in acute GVHD
Inducible co-stimulator (ICOS) interaction with its ligand (ICOSL) is involved in several T cell effector functions. While blockade of ICOS:ICOSL interaction in chronic graft versus host disease (GVHD) seems benefi cial, results for acute GVHD remain controversial. To further elucidate its role in a...
ORGANISM(S): Mus musculus 
2009-09-14 | E-GEOD-17995 | biostudies-arrayexpress
TranscriptomicsPRC2 in Ewing tumors
We found the PRC2 component EZH2 to be upregulated by the pathognomonic fusion oncogene EWS-FLI1 in Ewing tumors and mesenchymal stem cells (Richter GH et al., Proc Natl Acad Sci U S A. 2009;106:5324-9). Downregulation of EZH2 by RNA interference in Ewing tumor cell lines suppressed oncogenic transf...
ORGANISM(S): Homo sapiens 
2009-04-29 | E-GEOD-15757 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Hodgkin’s lymphoma cell lines with different sensitivity to cytotoxic drugs
By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. Furthermore, we tested the sensitivity of these cell lines for cytotoxic drugs (cisplatin, etoposide, melphalan) and compared the gene-expression profile of chemotherapy-resistant and -se...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-26325 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Hodgkin’s lymphoma cells
By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. RNA was extracted from established Hodgkin's lymphoma cell lines and analyzed with Affymetrix Human Exon 1.0ST microarrays.
ORGANISM(S): Homo sapiens 
2013-07-16 | E-GEOD-47686 | biostudies-arrayexpress
TranscriptomicsGene expression profile of Hodgkin’s lymphoma cells after knock-down of DUSP5
By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell line L-428 after knock-down of DUSP5 (dual specificity phosphatase 5) RNA was extracted from established Hodgkin's lymphoma cell line L-428 and hybridized with Affymetrix HG_U133A microarrays.
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-52831 | biostudies-arrayexpress
UnknownImmunogenicity of the Envelope Surface Unit of Human Endogenous Retrovirus K18 in Mice.
Not available
S-EPMC9369184 | biostudies-literature
TranscriptomicsGene expression in pediatric cALL
Common ALL (cALL) is the most frequent entity of childhood ALL and carries an early pre-B cell phenotype. Expression patterns of 25 pediatric cALL samples were analyzed by use of high-density DNA microarrays HG-U133A. Leukemic patients’ bone marrow samples were compared to sorted B cells from cord...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-34670 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of human ezh2 specific siRNA A673 treated cells reveals EZh2 is a mediator of EWS-FLI1 driven tumor growth blocking endothelial and neuro-ectodermal differentiation
Ewing Tumors (ET) are highly malignant tumors, localized in bone or soft tissue and are molecularly defined by ews/ets translocations. We identified histone methyl-transferase Enhancer of Zeste, Drosophila, Homolog 2 (EZH2) to be increased in ET. EZH2’s suppressive activity maintains stemness in n...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-12692 | biostudies-arrayexpress
UnknownThe histone variant H2A.Bbd is enriched at sites of DNA synthesis.
Not available
S-EPMC4041467 | biostudies-literature
UnknownElevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival.
Not available
S-EPMC5816752 | biostudies-literature
Sort   by:  
 Page size