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The goal of this experiment was to use global gene expression profiling to compare the global genetic reprogramming of spleen XCR1+ DC upon in vivo stimulation with a viral-type ligand, polyI:C which strongly induces type I interferons, versus with a ligand derived from an intracellular parasite whi...
ORGANISM(S): Mus musculus 
Single-cell RNA sequencing (scRNA-seq) on Treg cells from PBS and STAg treated mice
To identify cell composition and characterize transcriptional regulation in regulatory T (Treg) cells derived from mice subjected to soluble tachyzoite antigen (STAg) of Toxoplasma gondii treatment, we prepared splenic CD4+CD25+ Treg cells from PBS and STAg treated mice, and performed scRNA-seq usin...
ORGANISM(S): Mus musculus 
2020-12-31 | GSE132803 | GEO
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