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ProteomicsStimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish
Cardiac metabolism plays a crucial role in producing sufficient energy to sustain cardiac function. However, the role of metabolism in different aspects of cardiomyocyte regeneration remains unclear. Working with the adult zebrafish heart regeneration model, we first find an increase in the levels o...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2020-07-13 | PXD016235 | Pride
Metabolism Cardiac regeneration Yebrafish 
ProteomicsScreening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists
Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and diabetes. Here, we report the establishment, characterization and use of a vertebrate 'insulin-free' model to identify insulin-independent modulators of glucose metabolism. insuli...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2018-12-13 | PXD012027 | Pride
Chemical screen Metabolism Insuline mutant Zebrafish Glucose homeostasis 
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