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UnknownGenome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed a multi-ancestry meta-analysis of genome-wide association st...
S-EPMC11396662 | biostudies-literature
UnknownPsychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Psychiatric conditions share common genes, but mechanisms that differentiate diagnoses remain unclear. We present a multidimensional framework for functional analysis of rare copy number variants (CNVs) across 6 diagnostic categories, including schizophrenia (SCZ), autism (ASD), bipolar disorder (BD...
S-EPMC12338884 | biostudies-literature
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