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The purpose of this study was to improve prediction of patients at high-risk for metastatic disease utilizing a nested case-control design that uniquely enables enrichment for relevant phenotypes. We identified all women diagnosed with primary breast cancer from January 1, 1997, to December 31, 2005...
ORGANISM(S): Homo sapiens 
We aimed to study the impact of bacteria-derived metabolites in solid organ transplantation. The short-chain fatty acid butyrate was administered using a new drug-delivery method developed by Wang et al. (https://doi.org/10.1038/s41551-022-00972-5). This system is based on a micelle platform that ca...
ORGANISM(S): Mus musculus 
The experiment investigates how the azole fungicide prochloraz and the organochlorine insecticide endosulfan affect behavior and gene expression in the freshwater invertebrate Daphnia magna in order to distinguish endocrine from neurotoxic mechanisms and derive mechanistic information relevant for e...
ORGANISM(S): Daphnia magna 
The experiment investigates how the artificial sweetener acesulfame K and its photodegradation products affect the gene expression in the freshwater invertebrate Daphnia magna. Juvenile D. magna were subjected to an acute immobilization test (OECD Guideline 202) followed by RNA extraction and transc...
ORGANISM(S): Daphnia magna 
The experiment investigates how abamectin, chlorpyrifos, nicotine, pyriproxyfen and thiacloprid affect the gene expression in the freshwater invertebrate Daphnia magna. The experiment aimed to distinguish neurotoxic mechanisms and derive mechanistic information relevant for environmental risk assess...
ORGANISM(S): Daphnia magna 
The experiment investigates how the artificial sweetener sucralose affects gene expression in the teleost fish Danio rerio in order to derive mechanistic information relevant for environmental risk assessment. The main test including transcriptomics, was conducted with 10 µg/L and 100 mg/L as test c...
ORGANISM(S): Danio rerio 
The experiment investigates how the artificial sweetener sucralose affects behavior and gene expression in the freshwater invertebrate Daphnia magna in order to derive mechanistic information relevant for environmental risk assessment. Juvenile D. magna were first subjected to a behavioral swimming ...
ORGANISM(S): Daphnia magna 
The experiment investigates how the artificial sweetener sucralose affects gene expression in the teleost fish Danio rerio in order to derive mechanistic information relevant for environmental risk assessment. The main test including transcriptomics, was conducted with 10 µg/L and 100 mg/L as test c...
ORGANISM(S): Lemna minor 
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