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TranscriptomicsGenome-wide analysis of gene expression in VAV1-/- versus VAV1+/+ bone marrow (BM)-macrophages
Analysis of differential gene expression profiles in VAV1-/- versus VAV+/+ BM-macrophages , respectively. A distinct expression profile in VAV1-/- versus VAV1+/+ (wild-type) BM-macrophages allows to resolve molecular mechanisms. Total RNA was obtained froms BM-macrophages of VAV1+/+ and VAV1-/- mic...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-36123 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of the effect of cryopreservation on peripheral blood mononuclear cells
Analysis of cryopreservation effects on peripheral blood mononuclear cells at gene expression level. The hypothesis tested in the present study was that cryopreservation has an influence on the transcriptome profile of peripheral blood mononuclear cells. Results indicated remarkable changes in expre...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-24753 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of the effect of long-term freezing of PAXgene Blood RNA tubes
Analysis of long-term freezing on the stability of transcriptome profiles in PAXgene stabilized whole blood samples. In the present study it was tested if long-term freezing of PAXgene RNA tubes (up to one year) has an influence on the transcriptome profile of peripheral whole blood samples. Resul...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-24757 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in Krt1+/+ versus Krt1-/- epidermis and full-thickness skin.
Keratin 1 (KRT1) and its heterodimer partner keratin 10 (KRT10) constitute the intermediate filament cytoskeleton of suprabasal skin keratinocytes. They participate in formation of the epidermal barrier, which protects against dehydration and inflammation. Mutations in KRT1 cause keratinopathic icht...
ORGANISM(S): Mus musculus 
2012-12-01 | E-GEOD-32951 | biostudies-arrayexpress
TranscriptomicsTranscriptome wide analysis of classically and alternatively activated macrophages
Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived human M1- and M2-like macrophage profiling (RNA-seq) to microarray and quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods an...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-36952 | biostudies-arrayexpress
TranscriptomicsTranscriptome wide analysis of untreated, classically and alternatively activated macrophages
Analysis of human M0-, M1-, and M2-like macrophages. Total RNA was isolated from untreated, classically and aternative activated human macrophages
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-35449 | biostudies-arrayexpress
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