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ProteomicsPrimary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant brain tumor in infants and is characterized by loss of nuclear SMARCB1 protein expression. Recent studies show that AT/RTs comprise three molecular subgroups with epigenetic differences, including distinct expression patterns of g...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD027211 | Pride
Atypical teratoid/rhabdoid tumor Targeted therapy Stat1/dr5 signaling Primary cilia 
TranscriptomicsERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [RNAseq]
Interferon-gamma (IFNg) exerts potent growth inhibitory (antiproliferative/pro-apoptotic) effects on a wide range of tumors, including melanoma. While several terminal effectors of cell cycle arrest and apoptosis have been identified, a definitive account of the signaling pathway leading to these ev...
ORGANISM(S): Homo sapiens 
2023-10-06 | GSE235235 | GEO
OtherERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [CRISPR screen]
Interferon-gamma (IFNg) exerts potent growth inhibitory (antiproliferative/pro-apoptotic) effects on a wide range of tumors, including melanoma. While several terminal effectors of cell cycle arrest and apoptosis have been identified, a definitive account of the signaling pathway leading to these ev...
ORGANISM(S): Homo sapiens 
2023-10-06 | GSE235237 | GEO
GenomicsERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [RNAseq]
ERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [RNAseq]
PRJNA985598 | ENA
GenomicsERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [CRISPR screen]
ERK signaling plays an essential role in the IFNg-mediated apoptosis of melanoma cells. [CRISPR screen]
PRJNA985597 | ENA
TranscriptomicsPrimary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant brain tumor in infants and is characterized by loss of nuclear SMARCB1 protein expression. Recent studies show that AT/RTs comprise three molecular subgroups with epigenetic differences, including distinct expression patterns of g...
ORGANISM(S): Homo sapiens 
2022-09-19 | GSE179668 | GEO
UnknownPrimary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.
Not available
S-EPMC9489777 | biostudies-literature
GenomicsPrimary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
PRJNA744517 | ENA
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