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UnknownFunctional biology of the Steel syndrome founder allele and evidence for clan genomics derivation of COL27A1 pathogenic alleles worldwide.
Not available
S-EPMC7608441 | biostudies-literature
TranscriptomicsS. coelicolor Wild Type R5- Medium Time-course Study
Many biological processes are intrinsically dynamic, incurring profound changes at both molecular and physiological levels. Systems analyses of such processes incorporating large-scale transcriptome or proteome profiling can be quite revealing. Although consistency between mRNA and proteins is often...
ORGANISM(S): Streptomyces coelicolor 
2010-06-11 | E-GEOD-7172 | biostudies-arrayexpress
UnknownRare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank.
Not available
S-EPMC9402241 | biostudies-literature
ProteomicsRetinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina
Age-related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the loss of the retinal pigment epithelium (RPE) and photoreceptors and/or retinal and choroidal angiogenesis. Here we use AMD patient specific RPE cells with the Y402H high-risk polymorphism in the comp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-21 | MSV000088713 | MassIVE
TranscriptomicsS. coelicolor LY2517 R5- medium time course study
This SuperSeries is composed of the following subset Series: GSE21809: S. coelicolor LY2517 R5- medium time course study (Culture # 1) GSE21810: S. coelicolor LY2517 R5- medium time course study (Culture # 2) Refer to individual Series
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-21811 | biostudies-arrayexpress
TranscriptomicsS. coelicolor WL6268 R5- medium time course study
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-21808 | biostudies-arrayexpress
TranscriptomicsS. coelicolor YSK3654 R5- medium time course study
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-21807 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M752 SMM medium time course study
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-22398 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M145 SMM medium time course study
This SuperSeries is composed of the following subset Series: GSE22394: S. coelicolor M145 SMM medium time course study (Culture # 1) GSE22395: S. coelicolor M145 SMM medium time course study (Culture # 2) GSE22397: S. coelicolor M145 SMM medium time course study (Culture # 3) Refer to individual Ser...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-22399 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M145 SMM medium time course study (Culture # 2)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2012-12-19 | E-GEOD-22395 | biostudies-arrayexpress
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