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TranscriptomicsMutant analysis of C. elegans small RNAs, 5p-end-independent
These datasets profile the expression of small RNAs with 3p hydroxyls (including endo-siRNAs, miRNAs, and 21U-RNAs) in young adult worms from the wt and prg-1 mutant backgrounds. They were prepared using an approach that captures small RNAs independent of the covalent status of their 5p termini, as...
ORGANISM(S): Caenorhabditis elegans 
2008-06-15 | E-GEOD-11736 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary embryonic fibroblasts reveals the retinoblastoma binding protein RBP2 is an H3K4 demethylase
The roles of histone demethylase RBP2 in gene expression were assessed using gene expression profiling experiments with wild type and RBP2-/- primary MEFs. Several cytokine genes including SDF1 and Kit ligand were upregulated upon inactivation of RBP2. Experiment Overall Design: Total RNA were extr...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6945 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
TranscriptomicsMutant analysis of C. elegans small RNAs with 5p monophosphates
These datasets profile the expression of small RNAs with 5p monophosphates and 3p hydroxyls (including miRNAs, 21U-RNAs) in young adult worms from the wt, prg-1 mutant, and fog-2 mutant backgrounds. These datasets were prepared in the Craig C. Mello laboratory using T4 RNA ligase 1. Keywords: miRNA...
ORGANISM(S): Caenorhabditis elegans 
2008-06-15 | E-GEOD-11735 | biostudies-arrayexpress
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