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TranscriptomicsImmortalization capacity of HPV types is inversely related to chromosomal instability in immortal descendants.
Human papillomavirus (HPV) induced immortalization of human foreskin keratinocytes (HFK) is a two-step process, including 1) the bypass of replicative senescence and acquisition of an extended lifespan, and 2) the outgrowth of immortal cells. Our previous study showed that the immortalization capaci...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-72063 | biostudies-arrayexpress
TranscriptomicsIntegrated genomic and transcriptional profiling yields putative marker genes for cervical cancer
A better understanding of the consequences of recurrent (epi)genetic alterations that occur during cervical carcinogenesis is essential in the search for novel biomarkers. In this study we determined genome-wide expression profiles of 10 squamous cell carcinomas (SCCs), 5 adenocarcinomas (AdCAs) and...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6473 | biostudies-arrayexpress
TranscriptomicsIdentification of eight candidate target genes of the prognsotic 3p loss in cervical cancer by integrative genomic profiling
We performed integrative gene dosage and expression profiling to identify candidate target genes of the prognostic 3p loss in cervical cancer. Candidate target genes were proposed from the correlation between gene dosage and gene expression. Combined network, gene set, and gene ontology analysis of ...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-38964 | biostudies-arrayexpress
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