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TranscriptomicsResponse of Candida albicans towards a novel antifungal benzimidazole derivative
Fungal infections are a serious health problem in the clinic especially in the immunocompromised patient. Disease ranges from widespread superficial vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses only a limited arsenal of antimycotica are available,...
ORGANISM(S): Candida albicans 
2011-07-14 | E-GEOD-21622 | biostudies-arrayexpress
ModelsKrohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1
Krohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1 This model is described in the article: Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice. Krohn M, Lange C, Hofrichter J, Scheffler K, Stenze...
2024-09-02 | BIOMD0000000618 | BioModels
ModelsIL-1 Signaling
The pro-inflammatory cytokines interleukin 1 (IL-1) and 6 (IL-6) are crucially involved in the regulation of a multitude of physiological processes, in particular coordinating the immune response upon bacterial infection and tissue injury. Both interleukins induce complex signalling cascades and tri...
2214 | Cell Collective
ModelsIL-6 Signalling
The pro-inflammatory cytokines interleukin 1 (IL-1) and 6 (IL-6) are crucially involved in the regulation of a multitude of physiological processes, in particular coordinating the immune response upon bacterial infection and tissue injury. Both interleukins induce complex signalling cascades and tri...
2314 | Cell Collective
TranscriptomicsGenome wide analysis of Histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene
Epigenetic deregulation plays a critical role in the pathogenesis of Acute Myeloid Leukemia. But changes in histone modification patterns at the epigenome level still remain largely unknown. Here, we analyzed alterations of histone H3 acetylation patterns in a large number of patients with AML compa...
ORGANISM(S): Homo sapiens 
2011-12-16 | E-GEOD-27863 | biostudies-arrayexpress
TranscriptomicsMouse expression analysis
Comparison between APPPS1-FVB and APPPS1-FVBxABCC1ko mice Mouse brain expression analysis
ORGANISM(S): Mus musculus 
2011-07-18 | E-GEOD-30762 | biostudies-arrayexpress
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