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TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
GenomicsChIP-seq
Genome wide analysis RNA polymerase II (RNA Pol II) and histone marker H3K4me3 in hypoxia and normoxia using ChIP-seq. Breast cancer cell line (MCF-7) is cultured in normoxic condition (21% O2) and hypoxic condition (0.5%O2) for 16 hours. Immunoprecipitation of RNA Pol II and H3K4me3.
ORGANISM(S): Homo sapiens 
2014-02-10 | E-MTAB-1995 | biostudies-arrayexpress
TranscriptomicsRNA-seq
Comprehensive analysis of coding and non -coding transcriptome using ribo-depleted total RNA-seq and poly A selected RNA-seq of MCF-7 cells grown in hypoxia and normoxia. Breast cancer cell line (MCF-7) is cultured in normoxic condition (21% O2) and hypoxic condition (1%O2) for 24 hours. Expression...
ORGANISM(S): Homo sapiens 
2014-02-10 | E-MTAB-1994 | biostudies-arrayexpress
MetabolomicsLipidFrag: Improving reliability of in silico fragmentation of lipids and application to the Caenorhabditis elegans lipidome
Lipid identification is a major bottleneck in high-throughput lipidomics studies. We combined the in silico fragmentation tool MetFrag with LipidMaps lipid-class specific classifiers which calculate probabilities for lipid class assignments. The LipidFrag approach was then applied to MS/MS spectra o...
2017-03-09 | MTBLS291 | MetaboLights
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
UnknownThe caBIG® Life Science Business Architecture Model.
Not available
S-EPMC3087952 | biostudies-literature
UnknownDeep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging.
Not available
S-EPMC11806428 | biostudies-literature
GenomicsGenentech Data Access Committee
Data Access Committee EGAC00001000055
EGAC00001000055 | EGA
TranscriptomicsA family of secreted pathogenesis-related proteins in Candida albicans
Analyzing culture supernatants of yeast and hyphal cells of Candida albicans by mass spectrometry, we found two close homologues of pathogenesis-related (PR-) 1 proteins, Rbe1p and Rbt4p, in the secretome of this human pathogen. By sequence homology, we assigned three yet not characterized open read...
ORGANISM(S): Candida albicans 
2013-03-25 | E-GEOD-28212 | biostudies-arrayexpress
UnknownStandardization of Imaging Criteria for Detecting Macular Fibrosis in Neovascular Age-Related Macular Degeneration.
Not available
S-EPMC12830330 | biostudies-literature
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