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TranscriptomicsTranscription profiling of hematopoietic stem cells in the preleukemic phase from wiltype mice and mice deficient in transcription factor PU.1 to identify transcriptional changes preceding malignant transformation
Knockdown of the transcription factor PU.1 (Spi1) leads to acute myeloid leukemia (AML) in mice. We examined the transcriptome of PU.1 knockdown hematopoietic stem cells (HSC) in the preleukemic phase by linear amplification and genome-wide array analysis to identify transcriptional changes precedin...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-5654 | biostudies-arrayexpress
TranscriptomicsExpression data of diagnostic biopsy samples from Hodgkin lymphoma patients
Despite advances in Hodgkin lymphoma (HL) treatment, about 20% of patients still die due to progressive disease. Current prognostic models predict treatment outcome with imperfect accuracy, and clinically relevant biomarkers are yet to be established that improve upon the International Prognostic Sc...
ORGANISM(S): Homo sapiens 
2010-03-08 | E-GEOD-17920 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Hodgkin lymphoma cell line KMH2: Comparison of CIITA-BX648577 knockdown cultures with non-silencing controls
Description of differentially expressed genes between KMH2 CIITA-BX648577 knockdown cultures and non-silencing controls To determine the change in gene expression after siRNA interference with the fusion transcript CIITA-BX 648577 identified in KMH2 cells.
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25987 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of cell lines derived from classical Hodgkin lymphoma
Hodgkin lymphoma is derived from germinal center / post-germinal center B cells. To determine differentially expressed genes between Hodgkin Reed Sternberg cells and their presumed cell of origin we investigated the expression profiles of 5 commonly used Hodgkin lymphoma cell lines as compared to re...
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25986 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of D34+ BCR-ABL+ cells of CML patients in chronic phase or blast crisis to identify differentially expressed stage-specific genes
Profiling CD34+ BCR-ABL+ cells of CML patients in chronic phase or blast crisis to identify differentially expressed stage-specific genes.
ORGANISM(S): Homo sapiens 
2006-08-08 | E-MEXP-480 | biostudies-arrayexpress
UnknownGene expression-based model using formalin-fixed paraffin-embedded biopsies predicts overall survival in advanced-stage classical Hodgkin lymphoma.
Not available
S-EPMC3574267 | biostudies-literature
UnknownLymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival.
Not available
S-EPMC2745846 | biostudies-literature
TranscriptomicsGenome-wide profiling of follicular lymphoma by array comparative genomic hybridization
The secondary genetic events associated with follicular lymphoma (FL) progression are not well defined. We applied genome-wide BAC array comparative genomic hybridization to 106 diagnostic biopsies of FL to characterize regional genomic imbalances. Using an analytical approach that defined region...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-12393 | biostudies-arrayexpress
UnknownPrediction of Response to Systemic Corticosteroids in Active UC by Microbial Composition-A Prospective Multicenter Study.
Not available
S-EPMC10769779 | biostudies-literature
UnknownGray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations.
Not available
S-EPMC6368823 | biostudies-literature
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