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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
UnknownDe novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer.
Not available
S-EPMC8897191 | biostudies-literature
UnknownBacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction.
Not available
S-EPMC10529774 | biostudies-literature
UnknownSpread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term.
Not available
S-EPMC5756266 | biostudies-literature
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
ProteomicsTissue- and plasma-derived exosomal protein biomarkers define multiple human cancers
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of exosomes in 426 human samples from tissue explants (TE), plasma and other bodily fluids. Among traditional exosome markers, CD9, HSPA8, ALIX, HSP90AB1 represent ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-08-17 | PXD018301 | Pride
Exosomes  extracellular vesicles  proteomics  cancer  liquid biopsy  biomarkers  mass spectrometry  early cancer detection 
UnknownA genomic timescale for placental mammal evolution.
Not available
S-EPMC10233747 | biostudies-literature
GenomicsDrosophila melanogaster
Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins
PRJNA98389 | ENA
UnknownThromboprophylaxis for Children Post-Fontan Procedure: Insights From the UNIVERSE Study.
Not available
S-EPMC8751951 | biostudies-literature
UnknownMutations in WNT1 cause different forms of bone fragility.
Not available
S-EPMC3617378 | biostudies-literature
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