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TranscriptomicsGene signatures in prostate cancer linked to the Gleason score
The identification of novel oncogenic and druggable targets in patient subgroups with poor prognosis may help to develop corresponding targeted therapy approaches. Microarray data analyses of 59 prostate cancer and 39 benign tissue samples revealed major transcriptional differences. More than 5.000 ...
ORGANISM(S): Homo sapiens 
2012-10-19 | E-GEOD-32571 | biostudies-arrayexpress
TranscriptomicsMELK and UBE2C gene knockdown in prostate cancer cell line PC3
In order to address the putative role of MELK and UBE2C in prostate cancer development and progression, we performed functional analysis upon siRNA-based knockdown, and searched for downstream genes and processes by microarray experiments. RNAi-based inhibition of MELK and UBE2C was efficient in PC3...
ORGANISM(S): Homo sapiens 
2012-10-19 | E-GEOD-32873 | biostudies-arrayexpress
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